Correlates of suicidal ideation among HIV-positive persons

Columbia University, New York, New York, United States
AIDS (Impact Factor: 5.55). 06/2007; 21(9):1199-203. DOI: 10.1097/QAD.0b013e3281532c96
Source: PubMed


The present investigation sought to determine the extent to which demographic characteristics, illness-related burdens, alcohol and other substance use, and psychosocial factors are independently associated with suicidal ideation in HIV-positive individuals.
HIV-positive individuals in four US cities (San Francisco, Los Angeles, Milwaukee, and New York City) were screened between July 2000 and January 2002 for recruitment into a randomized behavioral prevention trial. Utilizing data from this screening visit, rates and correlates of suicidal ideation were examined in a diverse sample of 2909 HIV-positive individuals.
Using binary logistic regression study sites, demographic characteristics, illness-related burdens, alcohol and substance use, and psychosocial factors were entered as predictors of suicidal ideation. This cross-sectional model thus examined the independent effects of each factor.
Approximately one-fifth (19%) of participants reported thoughts of suicide in the past week. We observed that participants who were not heterosexual, rated HIV-related symptoms and medication side effects as more severe, reported regular marijuana use, and described elevated affective symptoms of depression were those who were more likely to report suicidal ideation. Conversely, participants who identified as Hispanic/Latino, individuals in a primary romantic relationship, and those who reported greater self-efficacy for coping were less likely to report suicidal ideation.
Suicidal ideation among HIV-positive individuals is relatively common and is associated with multiple factors. These independent correlates may assist with identifying HIV-positive individuals who are at increased risk of suicidal ideation so that they may be assessed regularly and referred for psychological treatment when appropriate.

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    • "Patients with HIV infection are at high risk for developing psychological disorders such as depression that significantly reduce their quality of life and may even result in suicidal attempts and death in severe cases (Carrico et al., 2007; Watkins and Treisman, 2015). The prevalence of major depressive disorder (MDD) has been estimated to be between 19 and 43%, on the basis of the studied population, and these patients are known to be two times more likely to suffer from MDD compared with the normal population (Ciesla and Roberts, 2001; Cysique et al., 2007; Gibbie et al., 2007). "
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    ABSTRACT: Patients with the HIV infection are at high risk for developing depression. The aim of this study was to investigate the safety and efficacy of antidepressant effects of minocycline on HIV patients with depression. Forty-six HIV patients, with mild-to-moderate depression and a Hamilton Depression Rating Scale (HDRS) up to 18, participated in a parallel, randomized, double-blind, placebo-controlled trial and underwent 6 weeks of treatment with either minocycline (100 mg twice daily) or placebo in the same manner. Patients were assessed using HDRS at baseline and at weeks 3 and 6. The primary outcome measure was to evaluate the efficacy of minocycline in improving depressive symptoms. General linear model repeated measures showed significant effect for time×treatment interaction on the HDRS score during the trial course [F(2, 88)=7.50, P=0.001]. There was no significant difference between the two groups regarding adverse events. No serious adverse event was reported. The administration of 100 mg minocycline twice daily seems to be safe and effective in improving depressive symptoms in HIV/AIDS patients with mild-to-moderate depression.
    Full-text · Article · Oct 2015 · International clinical psychopharmacology
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    • "Persons with HIV commonly experience an overwhelming severity of symptoms from both the disease and HIV medications.(10) Major depression is the psychiatric disorder most associated with HIV infection(11) and, along with substance use disorders, is highly predictive of suicidal ideation in PLWH.(12) Sleep disturbance is another very common symptom, experienced by as many as 73% of persons with HIV. "
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    Full-text · Article · Jun 2013 · International Journal of Therapeutic Massage & Bodywork Research Education & Practice
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    • "These independent correlates may assist identification of HIV-positive individuals whose risk of suicidal ideation is elevated. Accordingly, these persons can be assessed regularly and referred for psychological treatment where appropriate (Carrico et al., 2007). Endel obtained help: psychiatric during his depression and psychological in combating his pathological gambling; his dismissal from the army was a step-by-step process; he was given a civilian job. "
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    ABSTRACT: A former army officer unexpectedly killed his wife and two daughters by strangulation and afterwards hanged himself. Psychological autopsy (police investigation, forensic expertise, psychiatric records and interviews) showed how an ordinary young man, functioning well at work and normally in family life, had become a homicide–suicide perpetrator. The study brings out the complex of risk factors for suicidal crisis: violent and risk-taking behaviour, impulsivity, depression, attempted suicide, pathological gambling, debts, HIV, dismissal from active military duty and, finally, shame as a reaction to social decline. It remains unclear whether the motives for the familicide were predominantly altruistic or, rather, egoistic, i.e. behaviour characteristic of a major narcissistic suicide crisis. Evidently, there is no genuine altruistic/hostile dichotomy; motives for this domestic homicide–suicide are mostly mixed or blurred. Although the perpetrator received psychiatric and psychological help, there were several identifiable deficiencies in the chain of care, with implications for possible prevention.
    Full-text · Article · Feb 2011 · Journal of Forensic Psychiatry and Psychology
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