Hypersexuality After Right Pallidotomy for Parkinson’s Disease

Department of Neurology, University of California at Los Angeles, USA.
Journal of Neuropsychiatry (Impact Factor: 2.82). 02/2004; 16(1):37-40. DOI: 10.1176/jnp.16.1.37
Source: PubMed


The authors describe hypersexuality following atypical right pallidotomy for intractable Parkinson's Disease (PD). This patient and literature review suggest important roles for the pallidum in sexual behavior and dopamine in sexual arousal.

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    • "Marlowe et al. 1975; Ghika-Schmid et al. 1995). Hypersexuality and paraphilias have also been observed in conjunction with damage to subcortical structures such as the thalamus or hypothalamus (Cummings and Mendez 1984; Miller et al. 1986; Absher et al. 2000), the septum (Miller et al. 1986; Gorman and Cummings 1992), the hippocampus, (Mendez et al. 2000; Casanova et al. 2002), and the basal ganglia (globus pallidus; Mendez et al. 2004; striatum in Huntington disease; e.g. Dewhurst et al. 1970). "
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