Characteristics and healthcare costs of patients with fibromyalgia syndrome

Pfizer Inc., New York, New York, United States
International Journal of Clinical Practice (Impact Factor: 2.57). 09/2007; 61(9):1498-508. DOI: 10.1111/j.1742-1241.2007.01480.x
Source: PubMed


To examine the characteristics and healthcare costs of fibromyalgia syndrome (FMS) patients in clinical practice.
Using a US health-insurance database, we identified all patients, aged > or = 18 years, with any healthcare encounters for FMS (ICD-9-CM diagnosis code 729.1) in each year of the 3-year period, 1 July 2002 to 30 June 2005. A comparison group was then constituted, consisting of randomly selected patients without any healthcare encounters for FMS during this 3-year period. Comparison group patients were matched to FMS patients based on age and sex. Characteristics and healthcare costs of FMS patients and comparison group patients were then examined over the 1-year period, 1 July 2004 to 30 June 2005 (the most recent year for which data were available at the time of the study).
The study sample consisted of 33,176 FMS patients and an identical number in the comparison group. Mean age was 46 years, and 75% were women. FMS patients were more likely to have various comorbidities, including painful neuropathies (23% vs. 3% for comparison group), anxiety (5% vs. 1%), and depression (12% vs. 3%) (all p < 0.001); they also were more likely to have used pain-related pharmacotherapy (65% vs. 34% for comparison group; p < 0.001). Mean (SD) total healthcare costs over 12 months were about three times higher among FMS patients [$9573 ($20,135) vs. $3291 ($13,643); p < 0.001]; median costs were fivefold higher ($4247 vs. $822; p < 0.001).
Patients with FMS have comparatively high levels of comorbidities and high levels of healthcare utilization and cost.

Download full-text


Available from: Ariel Berger
  • Source
    • "Among FM patients, 20%–50% work few or no days despite being in their peak wage-earning years.6,7 Disability payments are received by 26%–55% of FM patients compared with the national average of 2% of patients who receive disability payments from other causes.7–9 Furthermore, health care costs are three times higher among FM patients compared with matched controls.9 "
    [Show abstract] [Hide abstract]
    ABSTRACT: Complementary and alternative medicine includes a number of exercise modalities, such as tai chi, qigong, yoga, and a variety of lesser-known movement therapies. A meta-analysis of the current literature was conducted estimating the effect size of the different modalities, study quality and bias, and adverse events. The level of research has been moderately weak to date, but most studies report a medium-to-high effect size in pain reduction. Given the lack of adverse events, there is little risk in recommending these modalities as a critical component in a multimodal treatment plan, which is often required for fibromyalgia management.
    Full-text · Article · Mar 2013 · Journal of Pain Research
  • Source
    • "In addition to the American College of Rheumatology's (ACR) classification criteria [2] which are still a subject of debate [3] [4], FM has been defined as a syndrome that includes multiple symptoms such as pain, fatigue, sleep disorders, morning stiffness, loss of functional capacity, and mood alterations, as well as problems with cognition, memory, and concentration. FM is a somatic syndrome that is more prevalent in women [5] and has been associated with a general decrease in quality of life [6], physical performance [7], and a greater use of healthcare resources [8]. "
    [Show abstract] [Hide abstract]
    ABSTRACT: Objective Fibromyalgia (FM) is characterized by a heterogeneous group of clinical symptoms that are evaluated using a wide variety of instruments. This study sought to develop and validate a new scale, the Comprehensive Rating Scale for Fibromyalgia Symptomatology (CRSFS), to facilitate the joint evaluation of the most frequent symptoms in patients with FM. Methods CRSFS items were based on a literature review and a focus group composed of patients and healthcare professionals. Four samples of patients (FM, non-FM rheumatic pain, depression, and healthy volunteers) were used to study the reliability and validity of the CRSFS. The factor structure of the CRSFS was determined through exploratory and confirmatory factor analyses. The test–retest and inter-examiner reliabilities were evaluated in a subsample of participants with FM. The criterion and convergent construct validity were compared using valid and reliable instruments to assess the impact of FM on quality of life, pain, fatigue, mood, and quality of sleep. The capacity to differentiate groups of patients was examined by comparing the CRSFS scores of the four samples to each other and using receiver operating characteristics curves. Results The sample was composed of 240 participants, the mean age was 49.1years (SD=10.4), and 97.5% of them were women. The factor analyses, as well as the tests of reliability and validity, were positive. The final version of the CRSFS consisted of 20 symptoms evaluated using 60 items. Conclusion The CRSFS is a valid and reliable 4-factor scale that evaluates the most frequent clinical symptoms of patients with FM.
    Full-text · Article · Feb 2013 · Journal of Psychosomatic Research
  • Source
    • "In addition to the personal consequences, substantial healthcare costs are accrued. For example, between 2002 and 2005, annual healthcare costs in the US were three times higher in people with FM versus those without FM [2]. Management of FM includes both pharmacologic and nonpharmacologic approaches [3]. "
    [Show abstract] [Hide abstract]
    ABSTRACT: Fibromyalgia is a major public health problem affecting an estimated 200 to 400 million people worldwide. The purpose of this study was to use the meta-analytic approach to determine the efficacy and effectiveness of randomized controlled exercise intervention trials (aerobic, strength training, or both) on tender points (TPs) in adults with fibromyalgia. Using random effects models and 95% confidence intervals (CI), a statistically significant reduction in TPs was observed based on per-protocol analyses (8 studies representing 322 participants) but not intention-to-treat analyses (5 studies representing 338 participants) (per-protocol, g, -0.68, 95% CI, -1.16, -0.20; intention-to-treat, g, -0.24, 95% CI, -0.62, 0.15). Changes were equivalent to relative reductions of 10.9% and 6.9%, respectively, for per-protocol and intention-to-treat analyses. It was concluded that exercise is efficacious for reducing TPs in women with FM. However, a need exists for additional well-designed and reported studies on this topic.
    Full-text · Article · Oct 2011
Show more