The proportion of individuals with obesity-induced hypertension among total hypertensives in a general Japanese population: NIPPON DATA80, 90
Department of Health Science, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu City, Shiga, 520-2192, Japan. European Journal of Epidemiology
(Impact Factor: 5.34).
09/2007; 22(10):691-8. DOI: 10.1007/s10654-007-9168-4
The increased prevalence of obesity in Japan may contribute to the high prevalence of hypertension in Japan. In the present study, we calculated the odds ratio for hypertension in obesity (body mass index (BMI) >or= 25.0 kg/m(2)) using data from independent nationwide surveys conducted in 1980 and 1990. We estimated the percentage of hypertensives whose condition was due to obesity among total hypertensives in the general Japanese population. In the 1980 survey, 18.8% of 4,623 male participants were obese and 50.4% were hypertensive, whereas 22.6% of 5,893 female participants were obese and 41.1% were hypertensive. For both sexes, obese participants had a higher odds ratio for hypertension than non-obese participants (BMI < 25.0 kg/m(2)), and there was a significant dose-response relationship between BMI and the odds ratio for hypertension. Among all hypertensives, the percentage whose hypertension was due to obesity in 1980 and 1990 was 11.4% (95% confidence interval (CI): 4.7-17.7%) and 15.3% (95% CI: 6.8-23.1%) for men and 19.3% (95% CI: 12.1-25.9%) and 22.3% (95% CI: 14.6-29.3%) for women, respectively. Approximately 80-90% of individuals with obesity-induced hypertension were in the 25.0 <or= BMI < 30.0 kg/m(2) category for both sexes in each year. In conclusion, we found that obesity-induced hypertension as a proportion of total hypertension increased between 1980 and 1990 for both sexes. Obesity now is playing a more important role in the high prevalence of hypertension in Japan than it was before.
Available from: Nobuyuki Shiba
- "Increased BMI is also associated with raised BP, glucose intolerance, dyslipidemia, and development of CVD in Japanese population. The analysis of NIPPON DATA showed that there was a significant dose–response relationship between the BMI and odds ratio for hypertension in men and women . This analysis also revealed that the percentage of individuals with hypertension attributable to obesity in 1980 and 1990 was 11.4% and 15.3% for men and 19.3% and 22.3% for women, respectively. "
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ABSTRACT: There are approximately 23 million patients with heart failure (HF) worldwide. The prognosis of patients with HF is still poor and a prospective approach for preventing and treating HF is necessary. The number of HF patients in Japan has been increasing since 1950 mainly because of a rapidly aging population. Furthermore, westernized dietary pattern, reduced physical activity, and obesity have become prominent, particularly in younger Japanese men. There is an increasing trend of diabetes and dyslipidemia, and the prevalence of smoking and hypertension continues to remain high. One of the largest HF cohorts in Japan, the CHART Studies, showed that coronary artery disease (CAD) was the most frequent etiology of HF currently. Thus, prospective strategies including accurate risk stratification, effective prevention of disease progression through evidence-based treatments, optimally personalized treatment particularly in elderly individuals, and life-long control of CAD risk factors are required to manage HF in Japan.
Available from: ncbi.nlm.nih.gov
- "Obesity is, of course, an important factor for high BP in Japanese, although Japanese people have been relatively lean compared with western people. The proportion of individuals with obesity-induced hypertension among total hypertensives was calculated using the baseline data of NIPPON DATA80 and NIPPON DATA90 . The estimated percentage whose hypertension was attributed by obesity (BMI ≥ 25 kg/m2) in 1980 and 1990 was 11% and 15% for men and 19% and 22% for women, respectively. "
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ABSTRACT: Japan is one of the countries with the longest longevity in the world, and it was accomplished by a drastic decline in stroke mortality from 1960's. The decline in stroke mortality would be largely explained by a population-wide decreasing trend in blood pressure (BP) level, because higher BP has been the strongest risk factor of stroke; about 20% of total deaths can be explained by higher BP above optimal in Japan. Decreasing trend in BP occurred both in men and women in all age-groups, which cannot be fully explained by the widespread use of anti-hypertensive agents. The most probable reason for the population-wide BP decline in Japan would be a large decline in dietary salt intake after 1950's. However, other factors including obesity, high alcohol intake, and unfavorable dietary habits could increase BP level of Japanese again.
Available from: Hirofumi Ohnishi
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ABSTRACT: Although abdominal obesity (AO) assessed by waist circumference (WC) is an important component of the metabolic syndrome (MetS), the usefulness of AO as a predictor of hypertension (HT) is not known. In this study, we investigated the incidence of HT in residents of two rural communities in Japan. The subjects were 187 men and 209 women selected from 712 residents who had undergone medical examinations in the towns of Tanno and Sobetsu, Hokkaido, in 1994 and 2002. Participants with HT in 1994 were excluded. Participants with AO were determined according to the WC criteria in the Japanese definition of MetS (> or = 85 cm for men, > or = 90 cm for women). The participants were divided into two groups: a non-AO group and an AO group. We compared the incidence of HT between the two groups and found a significantly higher incidence in the AO group. The results of logistic regression analysis showed that the relative risk of developing HT in individuals with AO was 2.33 (p = 0.017; 95% confidence interval [CI], 1.17-4.63) and that the risk per 1-cm increase in WC from 1994 to 2002 was 1.06 (p = 0.003; 95% CI, 1.02-1.10), both adjusted for several confounding factors. The results of this study suggest that, to prevent HT in Japanese, it is important to manage abdominal obesity and to monitor WC in individuals with or without abdominal obesity.
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