Promiscuous zinc-dependent acylase-mediated carbon?carbon bond formation in organic media

ArticleinChemical Communications 20(20):2078-80 · June 2007with11 Reads
Impact Factor: 6.83 · DOI: 10.1039/B700327G · Source: PubMed


    A zinc-dependent acylase, D-aminoacylase from Escherichia. Coli, displays a promiscuous activity to catalyze the carbon-carbon bond formation reaction of 1,3-dicarbonyl compounds to methyl vinyl ketone in organic media.