Mindfulness-Based Stress Reduction is associated with improved glycemic control in Type 2 diabetes mellitus: A pilot study

Department of Emergency Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Alternative therapies in health and medicine (Impact Factor: 1.24). 11/2006; 13(5):36-8.
Source: PubMed


Psychological distress is linked with impaired glycemic control among diabetics.
Estimate changes in glycemic control, weight, blood pressure, and stress-related psychological symptoms in patients with type 2 diabetes participating in a standard Mindfulness Based Stress Reduction (MBSR) program.
Prospective, observational study.
Academic health center.
Adult patients with type 2 diabetes mellitus.
Participation in MBSR program for heterogeneous patient population. Diet and exercise regimens held constant.
Glycosylated hemoglobin A1c (HA1c), blood pressure, body weight, and Symptom Checklist 90-Revised (anxiety, depression, somatization, and general psychological distress scores).
Eleven of 14 patients completed the intervention. At 1 month follow-up, HA1c was reduced by 0.48% (P = .03), and mean arterial pressure was reduced by 6 mmHg (P = .009). Body weight did not change. A decrease in measures of depression, anxiety, and general psychological distress was observed.

Download full-text


Available from: Jeffrey Greeson
  • Source
    • "For instance, psychological researchers have tended to focus on how the term mindfulness should be defined and applied (e.g.,Baer, 2003;Brown, Ryan, & Creswell, 2007;Dimidjian & Linehan, 2003;Germer, 2005), whereas medical researchers have been more interested in examining its tangible health benefits (e.g.,Grossman et al., 2004;Hoffman, Sawyer, Witt, & Oh, 2010;Kabat-Zinn, 2013) as well as its therapeutic effects on such International Journal of Psychological Studies Vol. 8, No. 1; 2016 conditions as Type 2 diabetes (Rosenzweig et al., 2007), fibromyalgia (Grossman et al., 2008), rheumatoid arthritis (Pradhan et al., 2007), chronic low back pain (Morone et al., 2008) and attention deficit hyperactive disorder (Zylowska, Smalley, & Schwartz, 2009). Moreover, we have in this article discussed some of the frequently used assessment scales. "
    [Show abstract] [Hide abstract]
    ABSTRACT: Over the past 20 years or so, the uptake of mindfulness within psychology, neuroscience and medicine has been celebrated as a new exciting development. It is within the realm of an assessment and therapeutic framework that mindfulness training has proved itself effective in terms of bettering the lot of many individuals. The primary purpose of this paper is to provide a brief review but also to undertake a more critical examination of the most common and popular forms of Western mindfulness intervention methods and the various scales that have been devised to measure their success in this regard.
    Preview · Article · Dec 2015
  • Source
    • "Even though a consensus about an unequivocal operational definition of mindfulness is lacking so far [12] [13], one of most commonly employed definitions of mindfulness was provided by Jon Kabat-Zinn who suggests that mindfulness could be described as a moment to moment awareness that is cultivated by purposefully paying attention to the present experience, with a non-judgmental attitude [14]. Interventions utilizing mindfulness techniques have shown efficacy for treating a variety of mental disorders and in coping with physical or medical conditions, including, among others, chronic pain [15], fatigue [16], stress [17] [18], cancer [19], heart disease [20], type 2 diabetes [21], psoriasis [22], and insomnia [23]. Mindfulness-based stress reduction (MBSR) [24] is a well-established mindfulness training that has shown to reduce stress, depression, and anxiety [25] [26]. "
    [Show abstract] [Hide abstract]
    ABSTRACT: An increasing number of mindfulness-based stress reduction (MBSR) studies are being conducted with nonclinical populations, but very little is known about their effectiveness. To evaluate the efficacy, mechanisms of actions, and moderators of MBSR for nonclinical populations. A systematic review of studies published in English journals in Medline, CINAHL or Alt HealthWatch from the first available date until September 19, 2014. Any quantitative study that used MBSR as an intervention, that was conducted with healthy adults, and that investigated stress or anxiety. A total of 29 studies (n=2668) were included. Effect-size estimates suggested that MBSR is moderately effective in pre-post analyses (n=26; Hedge's g=.55; 95% CI [.44, .66], p<.00001) and in between group analyses (n=18; Hedge's g=.53; 95% CI [.41, .64], p<.00001). The obtained results were maintained at an average of 19weeks of follow-up. Results suggested large effects on stress, moderate effects on anxiety, depression, distress, and quality of life, and small effects on burnout. When combined, changes in mindfulness and compassion measures correlated with changes in clinical measures at post-treatment and at follow-up. However, heterogeneity was high, probably due to differences in the study design, the implemented protocol, and the assessed outcomes. MBSR is moderately effective in reducing stress, depression, anxiety and distress and in ameliorating the quality of life of healthy individuals; however, more research is warranted to identify the most effective elements of MBSR. Copyright © 2015 Elsevier Inc. All rights reserved.
    Full-text · Article · Mar 2015 · Journal of Psychosomatic Research
  • Source
    • "A metaanalysis of 11 studies conducted between 1999 and 2003 (771 individuals, 388 of whom received MBSR) found consistently strong effect sizes in stress and anxiety reduction regardless of disease, in addition to reductions in depression, sleep, quality of life, and pain perception (Grossman, Niemann, Schmidt, & Walach, 2004). There have been additional studies that have noted disease-specific reductions in reported stress in patients with cardiovascular disease (Curiati et al., 2005; Griffiths et al., 2009; Parswani et al., 2013), irritable bowel syndrome (Gaylord et al., 2011; Zernicke et al., 2013), HIV/ AIDS (Duncan et al., 2012), diabetes (Rosenzweig et al., 2007), and cancer (Birnie, Garland, & Carlson, 2010; Minor, Carlson, Mackenzie, Zernicke, & Jones, 2006). One unique study in particular tested a brief mindfulness-based intervention for reducing psychological stress in patients before receiving psoriasis treatment (Kabat-Zinn et al., 1998). "
    [Show abstract] [Hide abstract]
    ABSTRACT: The aim of this article is to discuss how advanced practice nurses (APNs) can incorporate mindfulness-based stress reduction (MBSR) as a nonpharmacologic clinical tool in their practice. Over the last 30 years, patients and providers have increasingly used complementary and holistic therapies for the nonpharmacologic management of acute and chronic diseases. Mindfulness-based interventions, specifically MBSR, have been tested and applied within a variety of patient populations. There is strong evidence to support that the use of MBSR can improve a range of biological and psychological outcomes in a variety of medical illnesses, including acute and chronic pain, hypertension, and disease prevention. This article will review the many ways APNs can incorporate MBSR approaches for health promotion and disease/symptom management into their practice. We conclude with a discussion of how nurses can obtain training and certification in MBSR. Given the significant and growing literature supporting the use of MBSR in the prevention and treatment of chronic disease, increased attention on how APNs can incorporate MBSR into clinical practice is necessary. © The Author(s) 2015.
    Full-text · Article · Feb 2015 · Journal of Holistic Nursing
Show more