Masticatory dysfunction is associated with osteoporosis in older men

ArticleinJournal Of Clinical Periodontology 34(11):964-8 · December 2007with6 Reads
DOI: 10.1111/j.1600-051X.2007.01142.x · Source: PubMed
Thirty per cent of hip fractures occur in men. Nevertheless, the determinants of osteoporosis in men are unclear. Masticatory dysfunction is associated with malnutrition, and might represent an emergent cause of osteoporosis. The aim of this study was to assess the association of bone mineral density and self-assessed masticatory dysfunction in a general older population. We assessed the association of masticatory dysfunction with standard parameters of bone mineral density (T-score, Z-score and the stiffness index) in all 310 subjects aged 75+ living in Tuscania (Italy). Among men, self-assessed masticatory dysfunction was associated with T-score [beta=0.86, confidence intervals (CI)=0.15-1.57; p=0.019], Z-score (beta=0.86, CI=0.16-1.56; p=0.017) and the stiffness index (beta=9.12, CI=0.47-17.77; p=0.039) in linear regression modeling, after adjusting. No significant associations were observed in women. Masticatory dysfunction is independently associated with osteoporosis in elderly men. Evaluation of masticatory function should enter the routine assessment of older men with osteoporosis.
  • [Show abstract] [Hide abstract] ABSTRACT: Hypoxemia has been associated with low bone mineral density (BMD) in animal and human models. We assessed the association of haemoglobin levels with ultrasound-derived (UD) T score, Z score and the stiffness index in all 358 subjects aged 75+ living in Tuscania (Italy). Also, we searched for the haemoglobin cutoff levels that might best identify participants with osteoporosis. In the multivariable linear regression analysis, haemoglobin levels were associated among participants with the UD T score [beta = 0.13; 95% confidence interval (CI) = 0.01-0.25; p = 0.030], Z score (beta = 0.11; 95% CI = 0.01-0.22; p = 0.045) and stiffness index (beta = 1.87; 95% CI = 0.51-3.21; p = 0.007) after adjusting for potential confounders. Haemoglobin levels <140 g/L in men and <130 g/L in women best predicted osteoporosis in linear discriminant analysis. Haemoglobin is independently associated with all UD-BMD parameters. Haemoglobin levels <140 g/L in men and 130 g/L in women might be adopted in clinical practice to identify older subjects in whom screening for osteoporosis might yield higher effectiveness.
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  • [Show abstract] [Hide abstract] ABSTRACT: Because of the ageing of populations, disability has become an emergent problem from the clinical, social, and economic perspectives. Nevertheless, the determinants of disability in older subjects are still unclear. We assessed the association between self-assessed masticatory dysfunction (MD) and functional ability in older subjects. We analysed data of all 350 subjects aged 75+ living in Tuscania (Italy). Functional ability was estimated using the Katz' activities of daily living (ADLs), and the Lawton and Brody instrumental activities of daily living (IADLs) scales. MD was reported by 145 (41%) participants. Disability in the ADLs and IADLs was found in 37 (25%) and 53 (37%) of participants with MD, respectively, but only in 11 (5%) and 30 (15%) of the other participants (p<0.001). MD was associated with disability in the ADLs [odds ratio (OR)=2.40, 95% confidence interval (CI)=1.05-5.51], and IADLs (OR=2.77, 95% CI=1.07-7.16) in logistic regression, after adjusting. The association of MD with disability was stronger among subjects aged 80+. MD is independently associated with disability in community-dwelling elderly. Further studies are needed to evaluate the impact of early detection and correction of MD on the preservation of functional status in older populations.
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