DNA Linker-Mediated Crystallization of Nanocolloids

ArticleinJournal of the American Chemical Society 130(8):2442-3 · March 2008with17 Reads
Impact Factor: 12.11 · DOI: 10.1021/ja710710j · Source: PubMed

    Abstract

    Biofunctionalized nanocolloids offer a promising platform for creation of novel materials using bio-addressable interactions. Crystalline phases are of especial interest for the development of novel functional structures. We demonstrate that crystallization of nanocolloids can be achieved via hybridization of dispersed non-complementary single stranded DNA capped colloids with flexible single-stranded linker DNA. The crystalline structure belongs to body central cubic lattice and exhibits large thermal expansion. The evolution of the structure has been studied in details using in-situ small angle x-ray scattering. The formation of crystalline structures and reduced metastability are observed for systems with longer DNA linkers.