Recurrent Malignant Melanoma of the Penis

Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA.
Urology (Impact Factor: 2.19). 04/2008; 72(5):1185.e15-6. DOI: 10.1016/j.urology.2008.01.029
Source: PubMed


We report the case of a 72-year-old man with arcal-lentiginous type melanoma of the penis who had undergone local excision and bilateral inguinal lymphadenectomy but developed recurrence at the subcoronal ridge of the glans penis. To our knowledge, this is the 10th reported case in English published studies. We believe this case demonstrates the importance of close follow-up postoperatively and to beware of the recurrence of penile melanoma in patients without total penectomy.

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    ABSTRACT: Although the EAU guidelines for penile cancer suggest that the only mandatory imaging modality required is an ultrasound of the inguinal nodes,1 a variety of other radiological techniques can provide further information with regards to the extent of the primary tumor as well as metastatic disease. These techniques have an important role in both the oncological and surgical planning for the primary tumor as well as the inguinal and pelvic lymph nodes.
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    ABSTRACT: BACKGROUND: Although penile cancer is rare in developed countries, it occurs more frequently in other parts of the world and causes significant morbidity and mortality. OBJECTIVE: To review the current literature on the pathogenesis, risk factors, clinical presentation, staging, and treatment of premalignant and malignant tumors of the penis. MATERIALS AND METHODS: A literature review using PubMed was conducted searching for articles on penile malignancies. RESULTS: The majority of penile cancers are in situ or invasive squamous cell carcinomas, although other rare tumors of the penis occur, such as melanoma, basal cell carcinoma, extramammary Paget's disease, and soft tissue sarcomas. CONCLUSION: Physicians should be aware of the risk factors and clinical presentation of penile malignancies because early diagnosis is essential in effective management and cure. Accurate staging is imperative for risk stratification and treatment planning. Depending on the type of tumor, size of tumor, location, staging, and grading, treatment modalities vary and may include topical chemotherapy, surgical excision, Mohs micrographic surgery, laser excision or ablation, systemic chemotherapy, and radiotherapy.
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