Given that crucial psychological attributes of smartphone addiction have been studied in isolation from each other, we examined latent profiles of emotional distress (depression, stress, loneliness, and fear of missing out; i.e., FoMO); protective traits (self-control, mindfulness, grit); the behavioral inhibition system (BIS) and approach system (BAS; drive, reward responsiveness, and fun seeking) in relation to addictive smartphone use. We identified three distinctive profiles, using five fit statistics: AIC, BIC, adjusted BIC, an entropy, and LRT. The self-controlled, gritty, and mindful profile (22.7%) was characterized by heightened levels of self-control, grit, and mindfulness but lower levels of emotional distress, BIS, and BAS. The emotionally distressed profile (29.8%) was distinguished by elevated levels of depression, stress, loneliness, FoMO, and BIS, but relatively lower protective traits and BAS. Lastly, the approach sensitive profile (47.5%) corresponded to the normative group characterized by relatively higher BAS but mostly average levels of emotional distress and protective traits. When both global and pairwise comparisons between profiles were performed using Wald tests, we found that the self-controlled, gritty, and mindful profile was associated with significantly lower smartphone addiction tendencies than emotionally distressed or approach sensitive profiles, while the latter two did not differ from each other. These results still held when multiple covariates (age, sex, and income) were controlled for. Using a sophisticated person-centered approach, our findings underscore multidimensional psychological profiles that have different associations with smartphone addiction.