Copper-catalyzed addition of diboron reagents to alpha,beta-acetylenic esters: efficient synthesis of beta-boryl-alpha,beta-ethylenic esters.

ArticleinChemical Communications · March 2008with28 Reads
Impact Factor: 6.83 · Source: PubMed

    Abstract

    The efficient copper-catalyzed addition reaction of bis(pinacolato)diboron to alpha,beta-acetylenic esters has been developed, which produces the corresponding beta-borylated-alpha,beta-ethylenic esters in high yields under mild reaction conditions.