Vitiligo in the affected breast during neo-adjuvant chemotherapy for breast cancer

ArticleinBreast Cancer Research and Treatment 117(1):197-8 · August 2008with10 Reads
Impact Factor: 3.94 · DOI: 10.1007/s10549-008-0074-6 · Source: PubMed


    Dear Editor, We describe here a patient with breast cancer who developed vitiligo in the cancer-affected breast and axilla during neoadjuvant chemotherapy. A 41-year-old premenopausal woman was diagnosed with clinical stage II breast cancer after she discovered a left breast mass. Physical examination revealed a freely mobile 3 cm mass in the left breast 12 o’clock position and an area of induration in the left axilla. There were no associated skin changes. Biopsy of the breast mass confirmed hormone-receptor positive, highgrade invasive ductal carcinoma. A fine needle aspiration of the left axillary lymph node was also positive for carcinoma. The patient had a history of intermittent vitiligo which was not evident on skin examination at the time of diagnosis of breast cancer. She was treated with 4 cycles of