Trismus and Trigeminal Neuralgia in One Patient with Colon Cancer

Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, Mackay Medicine Nursing and Management College, Taipei, Taiwan.
Journal of the National Medical Association (Impact Factor: 0.96). 07/2008; 100(6):740-2. DOI: 10.1016/S0027-9684(15)31353-5
Source: PubMed


A 64-year-old man got trismus and trigeminal neuralgia under the diagnosis of colon cancer with mandibular metastasis after emergency appendectomy and elective hemicolectomy. The patient chose to forgo further surgery and was given only palliative chemotherapy and radiotherapy. He died six months after diagnosis. Metastatic tumors to the oral cavity are relatively uncommon. They are found most commonly in the mandible, and 70% of cases are adenocarcinoma-most commonly from breast and lung, followed by adrenals, kidneys, prostate, thyroid and colon. Mandibular mass is usually the first sign, then soft-tissue swelling, pain and paresthesias. Tissue proof is needed to confirm the diagnosis. The treatment depends on the nature of the primary, the degree of dissemination and the precise location. However, the prognosis is grim, with the mean survival after diagnosis being only about 6-7 months.

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