Socioeconomic Status and Incident Type 2 Diabetes Mellitus: Data from the Women's Health Study

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
PLoS ONE (Impact Factor: 3.23). 12/2011; 6(12):e27670. DOI: 10.1371/journal.pone.0027670
Source: PubMed


We prospectively examined whether socioeconomic status (SES) predicts incident type II diabetes (diabetes), a cardiovascular risk equivalent and burgeoning public health epidemic among women.
Participants include 23,992 women with Hb(A1c) levels <6% and no CVD or diabetes at baseline followed from February 1993 to March 2007. SES was measured by education and income while diabetes was self-reported.
Over 12.3 years of follow-up, 1,262 women developed diabetes. In age and race adjusted models, the relative risk of diabetes decreased with increasing education (<2 years of nursing, 2 to <4 years of nursing, bachelor's degree, master's degree, and doctorate: 1.0, 0.7 [95% Confidence Interval (CI), 0.6-0.8], 0.6 (95% CI, 0.5-0.7), 0.5 (95% CI, 0.4-0.6), 0.4 (95% CI, 0.3-0.5); p(trend)<0.001). Adjustment for traditional and non-traditional cardiovascular risk factors attenuated this relationship (education: p(trend) = 0.96). Similar associations were observed between income categories and diabetes.
Advanced education and increasing income were both inversely associated with incident diabetes even in this relatively well-educated cohort. This relationship was largely explained by behavioral factors, particularly body mass index.

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Available from: Jessica M Peña, Jan 16, 2014
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    • "Lower SES levels may be associated with a higher risk of incident diabetes, especially amongst women [10-15]. Previous studies suggest that levels of Hgb A1c in persons without diabetes may increase as socio-economic deprivation worsens [2,11,16], leading to the hypothesis that stress associated with deprivation may have an effect on glycemic control [2]. Most published studies in this area have used surveys or data collected for randomized controlled trials done for other purposes [2,11,16]. "
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