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Med Oral Patol Oral Cir Bucal. 2012 May 1;17 (3):e491-4. Object ive manifestat ions of teethi ng in children
e491
Journal section: Communit y and Preventive Dentistr y
Publication Types: Research
Teething disturbances; prevalence of objective manifestations in
children under age 4 months to 36 months
Roshan Noor-Mohammed 1, Sakeenabi Basha 2
1 MDS Reader, Department of Pedodontics and preventive dentistry, College of dental sciences, Davangere, Karnataka, India,
577004
2 MDS Reader, Department of Community Dentistry, College of dental sciences, Davangere, Karnataka, India, 577004
Correpondence:
Department of Pedodontics and Preventive Dentistr y
College of Dental Sciences
Davangere, Karnataka, India, 577004
drroshannm@yahoo.co.in
Received : 18/01/2011
Accepte d: 25/03/2011
Abstract
Objective: The aim of this study was to present data as responded by parents on teething manifestation dur-
ing eruption of primary teeth and the occurrence of objective manifestations in children ages 4 months to 36
months.
Settings and Design: Hospital based face-to-face questionnaire study.
Study Design: One thousand and one hundred children ages four to 36 months who had at least one erupting tooth
were included in the study. Parents were asked to complete a short questionnaire and children were then checked
by one of the authors.
Statistical analysis used: Chi-square analysis was performed to analyze information obtained. Level of signi-
cance was set at P<.05.
Results: There were 660 girls (60%) and 440 boys (40%) in the study. The most frequent clinical manifestations
were: Fever (16%), drooling (12%), diarrhea (8%), fever-drooling (15%), fever-diarrhea(8%) and drooling-diarrhea
(6%). In the study sample, boys demonstrated a higher prevalence of diarrhea than girls (P<.05). No statistical
signicance regarding other clinical manifestations and gender were observed. Teething manifestations were most
prevalent during the eruption of primary incisors. Occurrence of clinical manifestations in 4-12months and 13-24
months age was statistically signicant when compared with 25-36months age (P<0.05).
Conclusions: An association has been shown between general objective manifestations like fever (the most preva-
lent), drooling and diarrhea, and the eruption of primary teeth.
Most manifestations appeared during the eruption of the primary incisors.
Key words: Teething, primary teeth, eruption.
Noor-Mohammed R, Basha S. Teething disturbances; prevalence of ob-. Teethi ng disturbances; prevalence of ob-Teething dist urbances; prevalence of ob-
jective manifestations i n children under age 4 months to 36 months. Med
Oral Patol Oral Cir Bucal. 2012 May 1;17 (3):e491-4.
http://w ww.medicinao ral.com/medo ralfree01/v17i3/medora lv17i3p491.pdf
Article Number: 17487 http://www.medicinaoral.com/
© Medicina Oral S. L. C.I.F. B 96689336 - pISSN 1698-4447 - eISSN: 1698-6946
eMail: medicina@medicinaoral.com
Indexed in:
Science Citation Index Expanded
Journal Citation Reports
Index Medicus, MEDLINE, PubMed
Scopus, Embase and Emcare
Indice Médico Español
doi:10.4317/medoral.17487
http://dx.doi.org/doi:10.4317/medoral.17487
Med Oral Patol Oral Cir Bucal. 2012 May 1;17 (3):e491-4. Object ive manifestat ions of teethi ng in children
e492
Introduction
Teething is a natural physiological process that usually
occurs without problems. It consists of the migration of
the tooth from its intraosseous position in the jaw to
eruption in the oral cavity (1).
Some authors have associated primary tooth eruption
with alterations such as irritability, gingival irritation,
increased salivation, fever, agitated sleep, diarrhea, and
loss of appetite (2,3). These disturbances are respon-
sible for the referral of many babies to dental practi-
tioners, since they provoke discomfort and pain in the
patient. Parents always ask about the probable relation-
ship between these phenomena and the eruption of the
primary teeth.
The relationship between tooth eruption and organic
or systemic manifestations in children is controversial
among dentists and physicians within the literature (4).
It remains unclear whether the disturbances are caused
by the eruption of the primary teeth or whether they
simply coincide with tooth eruption. Since these dis-
turbances are mainly observed during the eruption of
the primary teeth, the objective of the present study was
to determine their occurrence in a population seen at a
child health institute and research centre.
Material and Methods
The study was conducted in the Child Health institute
and research centre. Children who visited the child
health institute over the period of six months were exam-
ined and one thousand and one hundred children were
selected who satised following inclusion criteria,
1. Children age between four months to 36 months
2. Displayed at least one tooth in the process of erup-Displayed at least one tooth in the process of erup-
tion. Eruption was determined if the clinical crown of
the tooth was visible, but not exceeding 3 mm exposure
above the gingiva.
Written consent was procured from all the parents who
participated in the study. Ethical clearance for the study
was procured from the ethical committee of the institu-
tion prior to the study. Data was obtained mostly from
the mothers who were the accompanying parent most
of the time. Parents were asked to complete a short and
simple questionnaire in local language. Information was
relayed in a yes/no manner about three objective mani-
festations noted during the eruption of the primary inci-
sors, canines, and molars, including drooling, diarrhea,
fever, and the combination of these symptoms. Drooling
was dened as excessive saliva coming out of the mouth
like bubbles or continuous salivation. Oral examination
of the child was done by one of the authors. Data was
analyzed using descriptive statistics. Chi-square analy-
sis was performed for the information obtained. Level
of signicance was set at P<.05.
Results
There were 660 (60%) girls and 440 boys (40%) in the
sample selected. Table 1 shows the distribution of the
clinical manifestations that were registered in the study.
In 32% of the children, no clinical manifestations were
noted. In 68% of children one or more of the symptoms
were registered. Each manifestation appeared alone or
in combination with others. The most frequent clinical
manifestations were: fever (16%), drooling (12%), di-
arrhea (8%), fever-drooling (15%), fever-diarrhea (8%),
drooling-diarrhea (6%) and the combination of fever-
drooling-diarrhea was found in 3% of the children.
Clinical manifestation Frequency Percentage
Fever 176 16
Drooling 132 12
Diarrhea 88 8
Fever-drooling 165 15
Fever-diarrhea 88 8
Drooling-diarrhea 66 6
Fever-drooling-diarrhea 33 3
No symptoms 352 32
Total 1100 100
Table 1. Distribution of the Cl inical Manifestations in the
Study Population.
In the study, boys demonstrated a signicantly higher
prevalence of diarrhea than girls (P<.05). No statisti-
cal signicance regarding other clinical manifestation
and gender were observed. Table 2 shows the clinical
manifestations that were present during the eruption
of the primary teeth according to the different type of
teeth. Individually fever was signicantly more preva-
lent during eruption of the incisors. (Table 3) shows the
frequency of clinical manifestations according to age.
Most clinical manifestations were observed between
the ages of 4 to 24 months. Mean age for reporting of
rst objective sign of teething was 7 ½ months. The
clinical manifestations decreased with age. Fever was
the most frequent clinical manifestation followed by
drooling and fever-drooling between the ages of 4 to12
months. Fever, drooling and fever-drooling were more
prevalent objective signs in study sample respectively.
Regarding the occurrence of clinical manifestations in
4-12months and 13-24 months age group there was no
statistical signicance (P>0.05). There was statistically
signicant difference on comparison of clinical mani-
festations between 4-12months group with 25-36months
age group (P<0.05) and 13-24months group with 25-36
months group children (P<0.05).
Med Oral Patol Oral Cir Bucal. 2012 May 1;17 (3):e491-4. Object ive manifestat ions of teethi ng in children
e493
Discussion
The studies on teething disturbances in children have re-
ported teething symptoms in as high as 80-90% of their
study population (5), the results of this study showed
that 68% of children with erupting teeth demonstrated
general systemic symptoms like drooling, diarrhea, and
fever, whereas 32% of study sample was asymptomatic.
These symptoms could appear alone or in a combination
with others. Lower percentage of teething symptoms
in this study may be due to not considering symptoms
such as irritability, gingival ir ritation and disturbed
sleep which are subjective in nature. The ndings were
in accordance with the results of previous studies (6-11).
The presence of fever alone and in combination of other
symptoms was 16% and 26% respectively. On the whole
fever reported in this study either alone or in combina-
tion was in high percentage of children (42%) which is
in accordance with the ndings of GaliIi et al. (8), Car-
penter (7), and Jaber et al. (9) who also showed a high
percentage of children with fever. Multiple tooth erup-
tions may establish a stress condition, during which the
resistance against infections is reduced and incidence of
infectious diseases is increased. Bennet and Brudno (12)
suggest that fever during the process of primary tooth
eruption is caused by the human teething virus (HT vi-
rus), which, at the beginning of life, is responsible for
a primary infection that becomes subclinical. The HT
virus remains in a latent state in the alveolar crypt until
its stimulation through eruptive movements, provoking
fever as well as local signs and symptoms such as gingi-
val inammation, hemor rhage, and pain (12).
This study showed that fever and drooling separately
and in combination were the most common manifesta-
tions accompanying the eruption of the incisors. Drool-
ing may be explained by the fact that the child agitates
the oral cavity, producing irritation and redness of the
gums (13).
The authors found that the clinical manifestations as-
sociated with the teething process decreased with age.
Most symptoms were found between the ages of 4 to 24
months, while fever, the most common manifestation,
was most prevalent between the ages of 4 to 12 months.
The authors could nd no explanation concerning the
nding that boys demonstrated signicantly higher
prevalence of diarrhea in the children under study.
Foster and Hamilton (14) have suggested that diarrhea
during tooth eruption is associated with the contamina-
tion of the baby’s ngers or objects put into the mouth.
There was statistically signicant result on compari-
son between 4-12months with 25-65months age group
Clinical manifestation Incisors (%) Canines (%) Molars (%)
Fever 9 3 4
Drooling 7 2 3
Diarrhea 2 1 5
Fever-drooling 8 2 5
Fever-diarrhea 3 1 4
Drooling-diarrhea 4 1 1
Fever-drooling-diarrhea 2 0 1
No symptoms 7 11 14
Total 42 21 37
Table 2. Prevalence of Clinical Manifestations According to Tooth-Type.
Clinical manifestation (n=395)
4months-
12months (%)
(n=387)
13months-
24months (%)
(n=318)
25months-
36months (%)
Fever 19.24 19.37 7.86
Drooling 15.25 11.68 8.49
Diarrhea 9.87 8.0 5.66
Fever-drooling 20 16.7 6.69
Fever-diarrhea 10.37 7.49 5.68
Drooling-diarrhea 10.12 5.26 1.88
Fever-drooling-diarrhea 4.55 3.1 0.94
No symptoms 10.6 28.4 62.8
Table 3. Prevalence of Clinical Manifestations According To Age.
[n= number of subjects]
Med Oral Patol Oral Cir Bucal. 2012 May 1;17 (3):e491-4. Object ive manifestat ions of teethi ng in children
e494
suggesting increased occurrence of clinical manifes-
tations during 4-12months age. Occurrence of clinical
manifestations was not statistically signicant between
4-12month and 13-24months. The dental and pediatric
literature presented different opinions regarding general
symptoms related to children’s teething, which were not
always data-based and were contradictory. The subjec-
tive nature of the information provided by the parents
was one of the reasons for this. It is difcult to separate
the signs and symptoms related to dental eruption from
changes in the behavior of the child based solely on the
parents’ subjective views. This was due to the extended
period of time of the teething. Drooling at the age of 4 or
5 months could have been associated with dental erup-
tion, but it also could have been a sign of the normal
activity of the salivary glands (15-17).
Despite the fact that there was an agreement about the
presence of symptoms during the eruption of primary
teeth, some authors totally objected to a cause-effect as-
sociation between them (17). It should be remembered
that coincidentally, primary tooth eruption begins when
infants lose mater nal antibody protection against bac-
teria and viruses; making the baby more vulnerable to
general threatening conditions as the newly pierced gin-
giva around an erupting tooth offers a convenient viral
infection site (18).
Focusing on the objective signs allowed the authors to
overcome a possible bias that could have been present
if the data were obtained solely from the parents, or if
other subjective symptoms would have been studied and
gleaned some light on this somewhat unsolved issue.
The study was limited by the study sample, which were
selected from the people visiting one particular child
health institute. This of course, may not be representa-
tive of whole of the population. Also, only three signs
were examined in the study: drooling, diarrhea and fe-
ver. Further research is needed on larger populations
and should include more signs. It should be noted, how-
ever, that before signs or symptoms of a potentially seri-
ous illness can be attributed to infants’ teething, other
possible causes must be ruled out. On the basis of the
results of this study, the authors arrived at the following
conclusions: a) An association has been shown between
general objective signs (drooling, fever, and diarrhea)
and the eruption of primary teeth with fever being the
most prevalent sign followed by drooling and fever-
drooling combination. b) Most signs appeared during
the eruption of the primary incisors. c) When an infant
at teething age has some symptoms, they may be at-
tributed to teething but other possible causes must be
ruled out rst.
References
1. Wake M, Hesket h K , Lucas J. Teething and tooth eruption in in-
fants: A cohor t study. Pediatrics. 2000;106:1374-9.
2. Macknin ML, Piedmonte M, Jacobs J, Skibinski C. Symptoms
associated w ith infant teething: a prospective study. Pediatrics.
2000 ;105:747-52.
3. Vaysse F, Noirrit E, Bailleul-Forestier I, Bah A, Bandon D. Er up-
tion and teething complications. Arch Pediatr. 2010;17:756-7.
4. Hulland SA, Lucas JO, Wake MA, Hesketh KD. Eruption of t he
primary dentition in human infants: a prospective descript ive study.
Pediatr Dent. 2000;22:415-21.
5. Cun ha RF, Pugliesi DM, Garcia LD, Murata SS. System ic and
local teething distu rbances: prevalence in a cli nic for in fants. J Dent
Child (Chic). 2004;71:24-6.
6. Wake M, Hesketh K , Allen M. Parent beliefs about infant teeth-
ing: a survey of Australian parents. J Paediatr Ch ild Health.
1999;35:446 -9.
7. Carpenter JV. The relationship between teethi ng and system ic dis-
turbances. ASDC J Dent Child. 1978;45:381-4.
8. Galili G, Rosenzweig KA, Klein H. Er uption of pri mar y teeth and
general pathologic cond itions. ASDC J Dent Child. 1969;36:51-4.
9. Jaber L, Cohen IJ, Mor A. Fever associated with teething. Arch Dis
Child. 1992;67:223-4.
10. Peretz B, Ram D, Hermida L, Otero MM. Systemic manifesta-
tions during erupt ion of primary teeth in infants. J Dent Child (Chic).
2003;70:170-3.
11. Feldens CA, Faraco IM, Ottoni AB, Feldens EG, Vítolo MR.
Teething symptom s in the rst year of life and associated factors: a
cohort st udy. J Clin Pediatr Dent. 2010;34:201-6.
12. Bennet HJ, Brudno DS. The teet hing virus. Pediatr Infect Dis.
1986;5:399-401.
13. Seward M H. General disturbances att ributed to eruption of the
human pr imary dent ition. ASDC J Dent Child. 1972;39:178-83.
14. Foster TD, Ha milton MC. Occlusion in the primary dentition.
Study of children at 2 and one-half to 3 years of age. Br Dent J.
1969;12 6:76-9.
15. Honig PJ. Teething--are today’s pediatricians using yesterday’s
notions? J Pediatr. 1975;87:415-7.
16. Coreil J, Price L, Barkey N. Recognition and management of
teething diar rhea among Florida pediatrician s. Clin Pediatr (Ph ila).
1995;34:591-8.
17. King DL. Teething revisited. Pediat r Dent. 1994;16:179-82.
18. Seward MH. Local disturbances attr ibuted to eruption of the hu-
man pri mar y dentition. A sur vey. Br Dent J. 1971;130:72-7.
Work attributed to: College of Dental Sciences and Bapuji Child
Health Institute and Research cent re, Davangere, Karnat aka, India