Palladium-Catalyzed C3-Benzylation of Indoles

Department of Chemistry, University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637, USA.
Journal of the American Chemical Society (Impact Factor: 12.11). 12/2011; 134(1):111-4. DOI: 10.1021/ja2095393
Source: PubMed


A general method for regioselective C3-benzylation of indoles has been developed. Various 3-substituted indoles and benzyl methyl carbonates with different electronic properties react under mild conditions to afford a diverse range of 3-benzylindolenine products in good yields.

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Available from: Ye Zhu, Feb 23, 2014
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