Cranial Fasciitis Presenting as an Intracranial Mass in a 10-Year-Old Girl

ArticleinPediatric and Developmental Pathology 15(2):146-50 · November 2011with11 Reads
Impact Factor: 0.87 · DOI: 10.2350/11-02-0990-CR.1 · Source: PubMed

    Abstract

    Cranial fasciitis is a mass-forming lesion of myofibroblastic proliferation of the skull and overlying soft tissue and occurs most frequently in pediatric patients. Cranial fasciitis has the same histological features as nodular fasciitis, which appears in the subcutaneous tissue in other parts of the body. Cranial fasciitis can involve the outer table of the skull, and it occasionally extends through the skull to form a mass involving both soft tissue and the epidural space. Intracranial cranial fasciitis without a soft tissue mass is extremely rare. Here, we report a case of a 10-year-old girl who presented with a massive intracranial mass that caused midline shift of the brain. The lesion showed focal areas of osseous metaplasia and a cytogenic abnormality of t(17;18)(q25∶q12.2) that have not yet been reported.