Aggressive angiomyxoma presenting as urinary retention in a male: A case report and literature review

Department of Surgery, Division of Urology, University of Kentucky, College of Medicine, Lexington, 40536-0298, USA.
The Canadian Journal of Urology (Impact Factor: 0.98). 10/2011; 18(5):5908-10.
Source: PubMed


We present a case of pelvic aggressive angiomyxoma presenting as urinary retention in a male. A 46-year-old male presented with urinary retention and was found on computed tomography (CT) scan of the pelvis to have a large pelvic tumor. A transrectal ultrasound guided needle biopsy of the tumor and prostate revealed a myxoid tumor; low volume, low grade prostate cancer was also detected. The patient underwent radical prostatectomy and excision of the pelvic tumor which was diagnosed as aggressive angiomyxoma (AAM). The patient was free of recurrence after 1 year of follow up. AAM is a benign myxoid tumor seen very rarely in males. Treatment consists of surgical excision with negative margins. Tumors variably express estrogen and progesterone receptors. Immunohistochemistry should be used to exclude other benign and malignant tumors. Patients should be followed with axial imaging as recurrence is common.

  • Source
    • "Therefore, it is important to distinguish AMF-like tumors from aggressive angiomyxoma. Aggressive angiomyxoma has been previously described in the scrotum, perineum and inguinal region of males and is associated with high risk of recurrence when incompletely resected, although, it is also an extremely rare tumor (21–25). Aggressive angiomyxoma is an aggressive neoplasm that usually shows an infiltrative growth pattern and invasive borders in contrast to the well-circumscribed lesions of AMF-like tumors. "
    [Show abstract] [Hide abstract]
    ABSTRACT: The purpose of the present study was to increase the knowledge of angiomyofibroblastoma (AMF)-like tumors in males by describing the second case of this rare lesion in the Chinese population with a long period of follow-up and by reviewing the literature. AMF-like tumor is a rare, circumscribed, slow-growing mesenchymal tumor that occurs predominantly in the vulva, perineum and pelvis of females. The present report presents a case of left scrotal AMF-like tumor in a 37-year-old male. Complete surgical excision was performed. The tumor was composed of spindle-shaped cells and small vessels proliferating in the edematous stroma. Immunohistologically, the tumor cells stained positive for smooth muscle actin and negative for S-100, CD34 and actin. Following seven years of follow-up the patient was asymptomatic and no evidence of tumor was found. In addition, the current literature was reviewed and the characteristics of this tumor were summarized. AMF-like tumors must also be distinguished from spindle cell lipoma, solitary fibrous tumor and aggressive angiomyxoma.
    Full-text · Article · Feb 2014 · Oncology letters