Article

High Diversity of the Saliva Microbiome in Batwa Pygmies

Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.
PLoS ONE (Impact Factor: 3.23). 08/2011; 6(8):e23352. DOI: 10.1371/journal.pone.0023352
Source: PubMed

ABSTRACT

We describe the saliva microbiome diversity in Batwa Pygmies, a former hunter-gatherer group from Uganda, using next-generation sequencing of partial 16S rRNA sequences. Microbial community diversity in the Batwa is significantly higher than in agricultural groups from Sierra Leone and the Democratic Republic of Congo. We found 40 microbial genera in the Batwa, which have previously not been described in the human oral cavity. The distinctive composition of the salvia microbiome of the Batwa may have been influenced by their recent different lifestyle and diet.

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Available from: Roland Schröder, May 26, 2015
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    • "However, before considering such a strategy further, it is pivotal to address possible influence of internal and external factors on the salivary bacterial composition. Previous studies have suggested that smoking[24]and other lifestyleassociated factors may have a general impact on the salivary microbiota242526. Unfortunately , little is known about if the salivary microbiome varies in composition over a 24 hour period, e.g., diurnal variation, and previous studies have reported conflicting results in relation to long stability of the salivary microbiota2728. "
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    • "The other observed genera include taxa that are not significantly represented in saliva microbiota previously reported. These studies and others indicate that the microbiota may adopt a relatively large number of configurations in both health and disease (Cephas et al., 2011; Nasidze et al., 2011; Luo et al., 2012; Ling et al., 2013). The phylogenetic representation of related species in bacterial communities confer functional redundancy since their genomes encode a relatively high frequency of homologous protein functions. "
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    Full-text · Article · Aug 2014 · Frontiers in Cellular and Infection Microbiology
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    • "This may include pathogenic organisms, such as Aggregatibacter actinomycetemcomitans, the causative agent of adolescent periodontal disease, which is common in those of African descent [50] and a member of a relatively abundant genus in the KhoeSan. Further study of the microbiomes associated with the KhoeSan and other diverse human populations (e.g., [51]), the microbiomic differences between these populations (e.g., [52,53]), especially across a variety of host physiological conditions, and the biology of commensal microbiota that are underrepresented in Western populations is needed to comprehensively differentiate the sources of variations observed between populations and to understand the coevolution between humans and their microbiome. "
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