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Chemical Composition and Antibacterial Activity of the Essential Oil of Lantana camara var. moritziana

Departamento de Farmacognosia y Medicamentos Orgánicos, Facultad de Farmacia y Bioanálisis, Universidad de Los Andes, Mérida, Venezuela 5101.
Natural product communications (Impact Factor: 0.91). 07/2011; 6(7):1031-4.
Source: PubMed

ABSTRACT

The essential oil obtained from the leaves of Lantana camara var. moritziana (Otto & Dietr.) López-Palacios collected at Rubio, Táchira State, Venezuela, was obtained by hydrodistillation in a Clevenger trap (0.1% yield). The oil was analyzed by gas chromatography-mass spectrometry (GC/MS) on HP GC-MS System, model 5973, identifying 33 compounds (97.1%) of which the major components were germacrene D (31.0%), followed by beta-caryophyllene (14.8%), a-phellandrene (6.7%), limonene (5.7%) and 1,8-cineole (5.2%). Evaluation of the antibacterial activity by agar diffusion method with discs against international reference bacteria (Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, Salmonella Typhi, Pseudomonas aeruginosa) showed growing inhibition of E. faecalis and S. aureus at MIC of 350 mg/mL and 400 mg/mL, respectively.

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    • "Moreover, L. camara has been proven to be one of the most easily available and cheap materials for the isolation of industrial essential oils famously known as Lantana oils (Randrianalijaona et al., 2005; Weyerstahl et al., 1999). Essential oils isolated from various parts of L. camara from different regions of the world have previously been studied (Filho et al., 2012; Kasali et al., 2004; Khan et al., 2002; Love et al., 2009; Ngassoum et al., 1999; Padalia et al., 2010; Sefidkon, 2002; Sundufu and Shoushan, 2004) and shown to possess various biological activities such as anti-inflammatory (Benites et al., 2009), antibacterial (Tesch et al., 2011), antioxidant (Sousa et al., 2013), insecticidal (Zoubiri and Baaliouamer, 2012b), allelopathic (Verdeguer et al., 2009) and larvicidal (Dua et al., 2010). Owing to the rapid propagation , invasive nature and abundant availability of L. camara, extensive research work in several parts of the world are going on in order to make this plant more useful for industrial applications (Passos et al., 2012; Patel, 2011; Sousa et al., 2013). "
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    ABSTRACT: The chemical components of essential oils derived from leaves and flowers of Lantana camara growing in Saudi Arabia are analyzed for the first time using gas chromatography techniques (GC–MS, GC–FID, Co-GC, LRI determination, and database and literature searches) on two different stationary phase columns (polar and nonpolar). This analysis led to the identification of total 163 compounds from leaves and flowers oils. 134 compounds were identified in the oil obtained from leaves of L. camara, whereas 127 compounds were identified in the oil obtained from flowers; these compounds account for 96.3% and 95.3% of the oil composition, respectively. The major components in the oil from leaves were cis-3-hexen-1-ol (11.3%), 1-octen-3-ol (8.7%), spathulenol (8.6%), caryophyllene oxide (7.5%) and 1-hexanol (5.8%). In contrast, the major compounds in the flowers oil were caryophyllene oxide (10.6%), b-caryophyllene (9.7%), spathulenol (8.6%), c-cadinene (5.6%) and trans-b-farnesene (5.0%). To the best of our knowledge, cis-3-hexen-1-ol and 1-octen-3-ol that were identified as major components in this study have not been reported earlier from Lantana oils.
    Full-text · Article · Jul 2015 · Arabian Journal of Chemistry

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    ABSTRACT: Objective The purpose of this study was to evaluate the essential oil composition as well as antibacterial activities of essential oil and leaves extracts of Lantana camara against five bacterial strains.Methods Essential oil was obtained by hydro-distillation from the leaves and analyzed by GC and GC-MS. The antibacterial activities of essential oil and the leaves extracts were tested by using disk diffusion method against five bacterial strains.ResultsThirty seven compounds were identified representing 98.11% of the total oil, of which trans-caryophyllene (13.95%), bicyclogermacrene (9.77%), ±-curcumene (8.57%), sabinene (8.28%), (E)-citral (6.90%), 1,8 cineole (5.06%), ±-pinene (4.03%), -terpinene (3.83%) and germacrene D (3.13%) were detected as major components. In respect to the antibacterial activities, essential oil showed the high degree of sensitivity against Micrococcus luteus, Escherichia coli, Staphylococcus aureus and Bacillus cereus except Pseudomonas aeruginosa while extracts of leaves obtained through petroleum ether, benzene, methanol and water exhibited good to moderate antimicrobial activity against all tested bacterial strains.Conclusions The present study suggested that M. luteus showed best zone of inhibition for the essential oil as well as aqueous extract among all the tested bacterial strains. The most active extract can be subjected to isolation of the therapeutic antimicrobials to carry out further pharmacological evaluation.
    No preview · Article · Dec 2012 · Asian Pacific Journal of Tropical Biomedicine
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