Mandibular Mucormycosis in Immunocompromised Patients: Report of 2 Cases and Review of the Literature

ArticleinJournal of oral and maxillofacial surgery: official journal of the American Association of Oral and Maxillofacial Surgeons 70(6):1362-8 · August 2011with16 Reads
Impact Factor: 1.43 · DOI: 10.1016/j.joms.2011.05.012 · Source: PubMed

    Abstract

    Mucormycosis, also known as zygomycosis, is an opportunistic fungal infection caused by a series of fungi in the Mucorales family in people with immune disorders. It is harmless to a healthy person, but when it has invaded the internal organs, it is frequently fatal in immunocompromised patients. It is known for having a very poor prognosis; however, with aggressive medical and surgical management, survival rates are currently thought to exceed 80%. It has 7 predominant clinical forms: rhinocerebral, pulmonary, cutaneous, gastrointestinal, central nervous system, disseminated, and, rarely, miscellaneous (ie, bone, kidney, cardiac, mediastinum, oral). Although oral involvement of this condition has been reported relatively frequently in the literature, mandibular involvement is a rarer condition than oral involvement. The purpose of this article is to report the treatment of isolated cases of mandibular mucormycosis and a review of the literature.