Differences in automated analyzers for assessing the use of imprecise serum chloride concentrations as indirect predictors of serum bromide concentrations

Department of Pediatrics, Uwajima City Hospital, Uwajima, Ehime, Japan. yamato
Epilepsy research (Impact Factor: 2.02). 06/2011; 96(1-2):158-60. DOI: 10.1016/j.eplepsyres.2011.06.001
Source: PubMed


Although bromide (Br) is used to treat intractable epilepsy, serum Br concentrations are not routinely analyzed. The present study measured serum Br(-) and Cl(-) concentrations in Br-treated epileptic patients, showing a significant correlation between Br(-) and imprecise Cl(-) concentrations, which suggested the use of a unique correlating equation for each diagnostic tool. Results indicated that imprecise Cl(-) concentrations are useful markers for measuring appropriate serum Br(-) levels in epileptic patients.

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