The gold industry standard for risk and cost of drug and vaccine development revisited

ArticleinVaccine 29(35):5846-9 · June 2011with8 Reads
Impact Factor: 3.62 · DOI: 10.1016/j.vaccine.2011.06.051 · Source: PubMed

    Abstract

    Gold dimensions of pharmaceutical drug development indicate that it takes on average 11.9 years, with an investment around US$ 0.8 Billion, to launch one product on the market. Furthermore, approximately 22% of the drug candidates successfully complete clinical testing. These universally acknowledged proportions largely originate from one single, much cited publication; Dimasi et al. [5]. However an additional six articles describing new chemical entities (NCE) development were identified, which contain little, if any, information on vaccines. Published cumulative success rates range from 7% to 78% and investments calculations span US$ 0.8 to 1.7 Billion. Obviously this disserves further clarification?