Cervical Cancer Incidence, Mortality, and Survival Among Asian Subgroups in California, 1990-2004

Public Health Institute, California Cancer Registry, Sacramento, California 95825, USA.
Cancer (Impact Factor: 4.89). 11/2008; 113(10 Suppl):2955-63. DOI: 10.1002/cncr.23752
Source: PubMed


Aggregated cancer statistics for Asians mask important differences in cancer burden among Asian subgroups. The purpose of this study was to describe the relative patterns of cervical cancer incidence, mortality, and survival among Chinese, Filipino, Japanese, Korean, South Asian, and Vietnamese women in California, using data from the California Cancer Registry.
All cervical cancer cases diagnosed among the 6 subgroups and non-Hispanic whites (NHW) from 1990 to 2004 were identified and used to calculate incidence and mortality rates and trends. The Kaplan-Meier method was used to calculate 5- and 10-year survival probabilities by subgroup, and Cox proportional hazards methodology was used to calculate survival differences adjusted for race and ethnicity, age, stage at diagnosis, socioeconomic status, and treatment factors.
Vietnamese and Korean women experienced greater cervical cancer incidence and mortality than NHW women, whereas rates among Chinese, Japanese, and South Asians were comparable or lower. Five-year unadjusted survival probabilities were greatest for South Asians (86%) and Koreans (86%), followed by Vietnamese (82%), Chinese (79%), and Filipinos (79%), as compared with NHW (78%) and Japanese (72%). The adjusted risk of cervical cancer death was significantly lower for South Asians, Koreans, Vietnamese, and Filipinos than for NHW women, but not for Chinese and Japanese.
Cervical cancer incidence rates vary substantially across the major Asian subgroups. Despite higher incidence and mortality rates compared with NHW women, Vietnamese, Koreans, and Filipinos have better survival outcomes. Further studies are needed to examine the factors behind these survival differences.

  • Source
    • "Accounted for one-third of the world's total annual new cases, 83.9% of cervical cancer in China accepted surgical treatment [2]. The situation of high surgical rate is similar for most patients worldwide in the past decade [2–4]. Radical hysterectomy (RH) with pelvic lymphadenectomy is the mainstay of surgical treatment for early stage cervical cancer and stage II endometrial cancer according to the guideline version 2011 of National Comprehensive Cancer Network [5, 6]. "
    [Show abstract] [Hide abstract]
    ABSTRACT: We aimed to investigate the preventive effects of acupuncture for complications after radical hysterectomy. A single-center randomized controlled single-blinded trial was performed in a western-style hospital in China. One hundred and twenty patients after radical hysterectomy were randomly allocated to two groups and started acupuncture from sixth postoperative day for five consecutive days. Sanyinjiao (SP6), Shuidao (ST28), and Epangxian III (MS4) were selected with electrical stimulation and Zusanli (ST36) without electrical stimulation for thirty minutes in treatment group. Binao (LI14) was selected as sham acupuncture point without any stimulation in control group. The main outcome measures were bladder function and prevalence of postoperative complications. Compared with control group, treatment group reported significantly improved bladder function in terms of maximal cystometric capacity, first voiding desire, maximal flow rate, residual urine, and bladder compliance, and decreased bladder sensory loss, incontinence, and urinary retention on fifteenth and thirtieth postoperative days. Treatment group showed significant advantage in reduction of urinary tract infection on thirtieth postoperative day. But no significant difference between groups was observed for lymphocyst formation. By improving postoperative bladder function, early intervention of acupuncture may provide a valuable alternative method to prevent bladder dysfunctional disorders and urinary tract infection after radical hysterectomy.
    Full-text · Article · Apr 2014 · Evidence-based Complementary and Alternative Medicine
  • Source
    • "Cervical cancer incidence and mortality fell in each group during this period. The APCs in the rates were −8.7% for Vietnamese, -5.1% among Koreans, -4.6% among Filipinos, -5.4% for Chinese and −2.3% among non-Hispanic Whites [10]. None of these studies related the trends in incidence or mortality with trends in cervical screening, which is largely opportunistic in the USA. "
    [Show abstract] [Hide abstract]
    ABSTRACT: Background Organised cervical screening, introduced in 1991, appears to have reduced rates of cervical cancer incidence and mortality in women in Australia. This study aimed to assess whether cervical cancer rates in migrant women in the state of New South Wales (NSW) showed a similar pattern of change to that in Australian-born women after 1991. Methods Data from the NSW Central Cancer Registry were obtained for females 15+ years diagnosed with invasive cervical cancer from 1973 to 2008 (N=11,485). We used joinpoint regression to assess annual percent changes (APC) in cervical cancer incidence and mortality before and after the introduction of organised cervical screening in 1991. Results APC in incidence fell more rapidly after than before 1991 (p<0.001) amongst women from seven groups defined by country of birth (including Australia). There was only weak evidence that the magnitude of this incidence change varied by country-of-birth (p=0.088). The change in APC in mortality after 1991, however, was heterogeneous by country of birth (p=0.004). For Australian and UK or Ireland-born women the mortality APC fell more rapidly after 1991 than before (p=0.002 and p=0.001 respectively), as it did for New Zealand, Middle East, North Africa and Asian-born (p≥0.05), but in other European-born and women from the ’Rest of the World’ it appeared to rise (p=0.40 and p=0.013 respectively). Conclusions Like Australian-born women, most, but not all, groups of migrant women experienced an increased rate of fall in incidence of cervical cancer following introduction of organised cervical screening in 1991. An apparent rise in mortality in women in a ‘Rest of the World’ category might be explained by a recent rise in migration from countries with high cervical cancer incidence and mortality rates.
    Full-text · Article · Oct 2012 · BMC Cancer
  • [Show abstract] [Hide abstract]
    ABSTRACT: Research on the incidence of cancer among the immigrant population has tended to be of quite a limited scope. We investigate whether immigrant women in the US are less likely to have been recently diagnosed with cancer, and what factors might help to explain any differences identified. We estimate multivariate Logistic regression models to identify the determinants of a diagnosis within the last 3years of any cancer, of breast cancer and of cervical cancer as well as the use of cancer screening by US women, using self-reported information on cancer diagnosis from consecutive waves of the US National Health Interview Survey over the years 1998–2007. Immigrant women of different ethnic groups are less likely to have been diagnosed with cancer, breast cancer and cervical cancer compared to US-born women. The use of basic health services, including cancer screening, is also lower for immigrant women for each main ethnic group. More research is required to determine whether immigrants may face delays in timely diagnosis of cancer by health care professionals. KeywordsCancer–Immigrant health–Minority women–Breast cancer–Cervical cancer–Cancer screening
    No preview · Article · Feb 2011 · Journal of Immigrant and Minority Health
Show more