Resolution of these issues should elucidate the molecular
mechanisms whereby c-Kit signaling is regulated and trans-
lated to particular biological outcomes.
This work was supported in part by grants from the Medical Re-
search Council of Canada and the National Cancer Institute of Canada
and by the Health Canada Bureau of Drug Research. Katherine A.
Siminovitch is a Senior Scientist and Robert Rottapel is a Research
Scholar of the Arthritis Society of Canada, and Louise Larose is a
recipient of a Medical Research Council of Canada/Canadian Re-
search Society scholarship.
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