Characterization of Human Ovarian Teratoma Hair by Using AFM, FT-IR, and Raman Spectroscopy

Department of Biomedical Engineering, College of Medicine, Kyung Hee University, Seoul, Korea.
Microscopy Research and Technique (Impact Factor: 1.15). 12/2011; 74(12):1121-6. DOI: 10.1002/jemt.21003
Source: PubMed


The structural, physical, and chemical properties of hair taken from an ovarian teratoma (teratoma hair) was first examined by atomic force microscopy (AFM), Fourier transform infrared (FT-IR), and Raman spectroscopy. The similarities and differences between the teratoma hair and scalp hair were also investigated. Teratoma hair showed a similar morphology and chemical composition to scalp hair. Teratoma hair was covered with a cuticle in the same manner as scalp hair and showed the same amide bonding modes as scalp hair according to FT-IR and Raman spectroscopy. On the other hand, teratoma hair showed different physical properties and cysteic acid bands from scalp hair: the surface was rougher and the adhesive force was lower than the scalp hair. The cystine oxides modes did not change with the position unlike scalp hair. These differences can be understood by environmental effects not by the intrinsic properties of the teratoma hair.

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