Association of sperm morphology and the sperm deformity index (SDI) with poly (ADP-ribose) polymerase (PARP) cleavage inhibition. Fertil Steril

Liverpool Women's Hospital, University of Liverpool, United Kingdom.
Fertility and sterility (Impact Factor: 4.59). 04/2011; 95(8):2481-4. DOI: 10.1016/j.fertnstert.2011.03.095
Source: PubMed


Apoptosis was induced in immature and mature sperm in the presence or absence of poly (ADP-ribose) polymerase (PARP) inhibitor. The association of cleaved (cPARP) with sperm morphology was examined using sperm deformity index (SDI) score. The SDI scores are associated with PARP cleavage as an early marker of apoptosis.

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