3T MR neurography using three-dimensional diffusion-weighted PSIF: Technical issues and advantages

The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins Hospital, 601 North Caroline Street, Room 4214, Baltimore, MD 21287, USA.
Skeletal Radiology (Impact Factor: 1.51). 04/2011; 40(10):1355-60. DOI: 10.1007/s00256-011-1162-y
Source: PubMed


Three-dimensional (3D) diffusion-weighted reversed fast imaging with steady state precession (3D DW-PSIF) MR sequence has the potential to create nerve-specific images. The authors describe the technical issues and their initial experience with this imaging technique employed for peripheral MR neurography.

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    • "It should be noted that 3D DW PSIF is a sensitive sequence; it is prone to motion and ghosting artifacts. However, MIP reconstructions can enhance apparent SNR and be used to elegantly demonstrate nerves in multiple planes (Figure 4) [3, 6, 20]. Since it is a steady state sequence with both T1 and T2 contrasts, it shows neuropathy and mass lesions as abnormal T2 hyperintensity, with normal nerves appearing isointense to muscles, similar to other anatomic spin echo type sequences. "
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