Hemato-Biochemical Alterations in Cross Bred Cattle Affected with Bovine Theileriosis in Semi Arid Zone

Pakistan Veterinary Journal (Impact Factor: 1.39). 01/2011; 31(2).
Source: DOAJ

ABSTRACT

This study was carried out to ascertain the changes in hematology and serum constituents in cross bred cattle affected with bovine theileriosis in semi arid zone of Pakistan. A total of 50 cross bred cows of age 2-5 years were included in the study. Twenty animals of same age were kept as healthy controls. The affected animals showed signs and symptoms of bovine theileriosis i.e., high rise in body temperature, general debility, enlarged prescapular lymph nodes, mucosal hemorrhages, conjunctivitis, etc. These animals were subjected to examination of peripheral blood smears for the presence of Theileria annulata schizonts in infected mononuclear cells and piroplasms in red blood cells. Significant (P≤0.05) decrease was observed in total erythrocyte counts, packed cell volume, hemoglobin, serum total proteins, albumin, globulins, glucose, calcium, phosphorus, cholesterol and triglycerides concentrations in cattle affected with bovine theileriosis compared with healthy controls, while significant (P≤0.05) increase was observed in serum bilirubin and alanine transaminase of affected cattle compared with healthy controls. Non significant differences were observed in serum magnesium and uric acid concentration in both affected and healthy controls. These observations revealed that bovine theileriosis caused by T. annulata in cross bred cattle in semi arid zone is associated with hemato-biochemical alterations.

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    • "Furthermore, hypo-proteinaemia may cause decrease in plasma albumin concentration and anorexia in infected animals (Singh et al. 2001), the proteinaceous fluids that accumulate in extra vascular spaces resulted from lymph nodes affected with Theileria (Stockham et al. 2000; Col and Uslu 2007). The minor rise of total bilirubin as well as urea concentration in Theileria-infected sheep was in accordance with findingsin bovine Theileriosisas reported by Singh et al. 2001; Col and Uslu 2007 and Khan et al., 2011.Destruction of infected erythrocytes in reticuloendothelial system and lymph nodes, liver dysfunction and haemolytic anemia synergistically increases the concentration of total bilirubin (Omer et al., 2002). Due to kidney damage the blood urea level rises (Col and Uslu 2007) and anorexia in Theileriosisresult in increased protein catabolism. "
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    ABSTRACT: Theileria is a tick-borne protozoan infesting wild and domestic ruminants globally. This research was conducted to evaluate hemato-biochemical alterations in Theileria infected Punjab Urial and domestic sheep and to study comparative efficiency of traditional screening methods with modern techniques. A total of 98 blood samples with thin blood smears of Urial and Domestic Sheep from Punjab, Pakistan with history of tick infestation, were collected and screened through microscopic techniques and PCR for Theileriosis respectively during summer 2013. Hematological parameters were analyzed by automatic hematology analyzer (Diatron Abacus) and Serum was analyzed by Semi-automatic Chemistry Analyzer (Micro Lab 300). Hematobiochemical findings revealed significant decrease (P<0.05) in Erythrocyte count, Leukocyte count, Hemoglobin Concentration, Pack Cell Volume, Total Proteins, Albumin and Creatinine in infected animals of both Urial and domestic sheep as compared with their control, while significant increase (P<0.05) in ALT, AST and Total Bilirubin was seen. Microscopic examination detected 47.6% of Urial and 35.6% of domestic sheep positive for Theileria while PCR analysis detected 54.7% positive samples in Urial and 51.7% in domestic sheep. This study concluded the basic data for values of hematology and serum biochemistry in Urial and domestic sheep with a higher susceptibility of Urial towards Theileriosis.
    Full-text · Article · Sep 2015 · Journal of Animal and Plant Sciences
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    • "Furthermore, hypo-proteinaemia may cause decrease in plasma albumin concentration and anorexia in infected animals (Singh et al. 2001), the proteinaceous fluids that accumulate in extra vascular spaces resulted from lymph nodes affected with Theileria (Stockham et al. 2000; Col and Uslu 2007). The minor rise of total bilirubin as well as urea concentration in Theileria-infected sheep was in accordance with findingsin bovine Theileriosisas reported by Singh et al. 2001; Col and Uslu 2007 and Khan et al., 2011.Destruction of infected erythrocytes in reticuloendothelial system and lymph nodes, liver dysfunction and haemolytic anemia synergistically increases the concentration of total bilirubin (Omer et al., 2002). Due to kidney damage the blood urea level rises (Col and Uslu 2007) and anorexia in Theileriosisresult in increased protein catabolism. "
    [Show abstract] [Hide abstract]
    ABSTRACT: Theileria is a tick-borne protozoan infesting wild and domestic ruminants globally. This research was conducted to evaluate hemato-biochemical alterations in theileria infected Punjab Urial and domestic sheep and to study comparative efficiency of traditional screening methods with modern techniques. A total of 98 blood samples with thin blood smears of Urial and Domestic Sheep from Punjab, Pakistan with history of tick infestation, were collected and screened through microscopic techniques and PCR for Theileriosis respectively during summer 2013. Hematological parameters were analyzed by automatic hematology analyzer (Diatron Abacus) and Serum was analyzed by Semi-automatic Chemistry Analyzer (Micro Lab 300). Hematobiochemical findings revealed significant decrease (P<0.05) in Erythrocyte count, Leukocyte count, Hemoglobin Concentration, Pack Cell Volume, Total Proteins, Albumin and Creatinine in infected animals of both Urial and domestic sheep as compared with their control, while significant increase (P<0.05) in ALT, AST and Total Bilirubin was seen. Microscopic examination detected 47.6% of Urial and 35.6% of domestic sheep positive for Theileria while PCR analysis detected 54.7% positive samples in Urial and 51.7% in domestic sheep. This study concluded the basic data for values of hematology and serum biochemistry in Urial and domestic sheep with a higher susceptibility of Urial towards Theileriosis.
    Full-text · Article · Sep 2015 · Journal of Animal and Plant Sciences
  • Source
    • "Furthermore, hypo-proteinaemia may cause decrease in plasma albumin concentration and anorexia in infected animals (Singh et al. 2001), the proteinaceous fluids that accumulate in extra vascular spaces resulted from lymph nodes affected with Theileria (Stockham et al. 2000; Col and Uslu 2007). The minor rise of total bilirubin as well as urea concentration in Theileria-infected sheep was in accordance with findingsin bovine Theileriosisas reported by Singh et al. 2001; Col and Uslu 2007 and Khan et al., 2011.Destruction of infected erythrocytes in reticuloendothelial system and lymph nodes, liver dysfunction and haemolytic anemia synergistically increases the concentration of total bilirubin (Omer et al., 2002). Due to kidney damage the blood urea level rises (Col and Uslu 2007) and anorexia in Theileriosisresult in increased protein catabolism. "

    Full-text · Article · Jan 2015 · Journal of Animal and Plant Sciences
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