Abdominal and Pelvic Coccidioidomycosis

Section of Infectious Diseases, University of Arizona College of Medicine, Tucson, Arizona, USA.
The American Journal of the Medical Sciences (Impact Factor: 1.39). 02/2011; 341(4):308-11. DOI: 10.1097/MAJ.0b013e3182058736
Source: PubMed


Coccidioidomycosis is a fungal infection endemic to the Southwestern United States that has a clinical presentation resembling community-acquired pneumonia. Disease occurs after inhalation of airborne arthroconidia. Dissemination to a variety of organ systems via hematogenous spread from a primary pulmonary focus may then occur. Coccidioidomycosis rarely involves the abdominal cavity. The authors review the spectrum of abdominal and pelvic presentations of coccidioidomycosis and report 6 unusual cases, including acute appendicitis, hepatitis and adnexal masses. Pathologists played a critical role in the diagnosis of these presentations by recognizing spherules in tissue. In only 2 of the cases were Coccidioides species cultured.

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