Lichen Sclerosus et Atrophicus with Cutaneous Distribution Simulating Lichen Planus

Article (PDF Available)inCase Reports in Dermatology 2(1):55-59 · April 2010with31 Reads
DOI: 10.1159/000313821 · Source: PubMed
Lichen sclerosus (LS) et atrophicus is a disease of unknown etiology, although hereditary, endocrine, and autoimmune factors are known to be involved. While the anal and genital regions are predominantly affected, only 2.5% of patients present with extragenital lesions, particularly of the trunk, neck, and upper limbs. The possible relationship between lichen sclerosus et atrophicus and both lichen planus (LP) and localized scleroderma (morphea) has not been clearly established, although in a number of cases, several of these conditions have been found simultaneously. We report the case of a 31-year-old woman with LS lesions affecting the neck, upper back, wrist and dorsum of the feet. The unusual character of this presentation is pointed out, along with its clinical similarity to LP.

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    • "Ekstragenital yerleşimlerde koebnerizasyon sıktır [2,6]. Vazquez ve ark. [7] el bileği ve ayak dorsumunda likenoid papulleri olan ve klinik olarak liken planusu düşündüren bir olgu sunmuşlardı. Olgumuzda el bilekleri ve ayak dorsumunda papüler hiperkeratotik lezyonları olması nedeniyle bu vaka ile klinik ve histolojik olarak benzerlik göstermekteydi. "
    Full-text · Article · Jan 2015
  • [Show abstract] [Hide abstract] ABSTRACT: Background: Little is currently known about the dermoscopic patterns of genital and extragenital lichen sclerosus (LS). In order to evaluate and compare the dermoscopic and histopathologic patterns of genital and extragenital lichen sclerosus, a retrospective analysis of clinical, dermoscopic and histopathologic features of genital and extragenital LS, collected between March 2010 and December 2011 at four dermatology clinics in Greece, Italy, Serbia and Uruguay was performed. Observations: A total of 29 lesions from 14 (mean age 62.8 years) and 12 (mean age 53.5 years) patients with genital and extragenital LS, respectively were analyzed. Mean duration of disease was 3.5 years for genital and 1.8 years for extragenital LS. White-yellowish structureless areas were seen in all cases of genital and extragenital LS; however linear vessels occurred at higher frequency in genital than in extragenital lesions (85.7% vs. 33.3%, respectively). Extragenital LS revealed two different time-related patterns: keratotic plugs were more prevalent in lesions with short duration (<2 years), whereas longer persisting lesions appeared atrophic and revealed fine chrysalis structures. Conclusions: Our morphologic study provides novel insights into the morphologic diversity of LS at different body sites and different stages of progression.
    Full-text · Article · May 2012
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