During the last millennia, climate changes and sea level raises strongly influenced N-W Europe environments. In the transition of the last glacial period to the present time, to these forcing factors, anthropogenic impacts were added. All of these factors are responsible for erosional crises and subsequently sedimentations. Several studies in the Lower Seine Valley were done to understand depositional environments during the Holocene infilling. In all of these studies, archaeological works were added on the Seine River tributies to have a better comprehension of the sedimentary response for every forcing factor in all of the Seine River system. Based on these studies, carried in different sections of the Lower Seine Valley, we made a first summary in order to understand the evolution of erosion/sedimentation couple. This couple, triggered by several forcing, is differently expressed in all the sectors of the Seine River and can be correlated to the most important climatic events at the global scale and to the important stages of Human development activities at the local scale.