Digitalization has long since entered and transformed our professional lives, our interaction with companies, and our private lives. With the progress in digitalization in general and of individuals in particular, both opportunities and challenges arise. Digitalization represents a double-edged sword, with its vast potential on the one end and a number of risks and detrimental effects for individuals, such as technostress, on the other. Individuals need to navigate the opportunities provided by digitalization, as well as its risks, in all areas of their lives. Addressing digitalization in a way that is in the best interest of individuals requires a thorough understanding of developments, challenges, and possible interventions and solutions. Matt et al. (2019) propose a framework for studying the digitalization of individuals, which represents a holistic approach to structure, classify, and position research along different roles of individuals from a comprehensive set of research angles. By applying this framework as a guiding structure, this dissertation aims to advance knowledge for an improved, safer, and more deliberate navigation of digitalization for individuals in their roles as employees, customers, and themselves from the research angles design, behavior, and consequences. While building on and integrating qualitative research methods such as literature analysis and expert interviews, this dissertation mainly relies on the collection of empirical data and their quantitative analysis. This comprises several small- and large-scale surveys and field experiments, as well as analytical methods such as structural equation modeling, regression analysis, and cluster analysis. Chapter 2 of this dissertation discusses the digitalization of individuals in their role as employees. Chapter 2.1 covers workplace design in terms of equipment with digital workplace technologies (DWTs) and the user behavior of employees. It determines which DWTs exist and are used by individual employees in a comprehensive and structured fashion. Contributing to a deeper understanding of workplace digitalization, chapter 2.1 also demonstrates and elaborates how this overview of DWTs represents a basis for individualized digital work design as well as adequate interventions. Chapter 2.2 deals with the consequences of DWT user behavior. It focuses on the relationship between workplace digitalization, the negative consequence technostress, and possible countermeasures termed technostress inhibitors. By enabling a more detailed understanding of the underlying mechanisms as well as evaluating the effects of countermeasures, chapter 2.2 discusses the overall finding that workplace digitalization increases technostress. The dynamics of its different components and technostress inhibitors, however, require individual consideration at a more detailed level, as the interrelationships are not consistently intuitive. In chapter 3, the focus changes to individuals in their role as customers. As a response to increasing data collection by companies as well as increasing data privacy concerns of customers, chapter 3.1 focuses on the identification of a comprehensive list of data privacy measures that address these concerns. Furthermore, it is identified that the implementation of some of these measures would lead to increased customer satisfaction, demonstrating that there is an upside to data privacy for companies and that mutually beneficial outcomes for both involved parties are conceivable. Chapter 3.2 analyzes whether and how digital nudging can be applied to influence customers online shopping behavior towards the selection of more environmentally sustainable products in online supermarkets and how this influence differs with respect to individual customer characteristics. It determines the digital nudging element default rules to be generally effective and simplification to be effective among environmentally conscious customers. On a macro level, the findings contribute to a safer environment in which individuals live their lives, while at the individual level, they foster decision-making quality and health. Chapter 4 highlights the digitalization of individuals themselves. Chapter 4.1 deals with the design of a habit-tracking app that offers users autonomy in their goal-directed behavior. It is found that the provision of autonomy enhances well-being. Its exercise improves performance, which in turn positively affects well-being. Chapter 4.1 thus contributes insights into how digital technologies can foster the flourishing of users. As a summary, this dissertation aims to provide research and practice with contributions to a deeper understanding of how individuals as employees, customers, and themselves can successfully navigate digitalization.