Article

Schwannoma Mimicking Laryngocele

Department of Otorhinolaryngology, College of Medicine and Research Center for Sensory Organs, Medical Research Center, Seoul National University, Seoul, Korea.
Clinical and Experimental Otorhinolaryngology (Impact Factor: 0.85). 09/2010; 3(3):166-71. DOI: 10.3342/ceo.2010.3.3.166
Source: PubMed

ABSTRACT

A schwannoma of the larynx is a rare benign tumor that usually presents as a submucosal mass in the pyriform sinus and the aryepiglottic space, and this type of schwannoma constitutes a diagnostic and therapeutic challenge for otolaryngologists. We present here two cases of supraglottic schwannomas that were misdiagnosed as laryngoceles. Both were excised through a lateral thyrotomy approach without a tracheostomy, and the laryngeal function was successfully maintained. We discuss the clinical and imaging findings and the management of this rare neoplasm with focusing on the differential diagnosis of laryngeal schwannoma and laryngocele. We also review the relevant medical literature.

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    • "CT scan is used to define the extent of the lesion and its anatomic relationships [12]. The differential diagnosis includes internal laryngocele [13] and laryngeal cist [7]. At magnetic resonance imaging (MRI), T1-weighted imaging of schwannoma shows high enhancement after gadolinium injection. "
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    ABSTRACT: Schwannoma is a neurogenic benign tumour arising from the proliferation of Schwann cells present in the peripheral nerve sheath of myelinated nerves. This proliferation can hypothetically appear in every anatomic region of the human body, but the nerve sheath tumors rarely occur within the larynx. In this paper the authors discuss the case of a 74-year-old female who presented to Emergency Unit (EU) for an important acute respiratory distress. Airway flexible endoscopy revealed a bulky mass of the aryepiglottic fold measuring 3.5 cm in diameter. The patient underwent tracheotomy and a single-step surgical excision treatment of the mass which was recognized as a schwannoma at pathological examination. Tracheotomy was closed 2 weeks postoperatively. After 18 months of followup, the patient is alive and free of disease and her voice had improved markedly.
    Full-text · Article · May 2012 · Case Reports in Medicine
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    • "CT scan is used to define the extent of the lesion and its anatomic relationships [12]. The differential diagnosis includes internal laryngocele [13] and laryngeal cist [7]. At magnetic resonance imaging (MRI), T1-weighted imaging of schwannoma shows high enhancement after gadolinium injection. "
    [Show abstract] [Hide abstract]
    ABSTRACT: Schwannoma is a neurogenic benign tumour arising from the proliferation of Schwann cells present in the peripheral nerve sheath of myelinated nerves. This proliferation can hypothetically appear in every anatomic region of the human body, but the nerve sheath tumors rarely occur within the larynx. In this paper the authors discuss the case of a 74-year-old female who presented to Emergency Unit (EU) for an important acute respiratory distress. Airway flexible endoscopy revealed a bulky mass of the aryepiglottic fold measuring 3.5 cm in diameter. The patient underwent tracheotomy and a single-step surgical excision treatment of the mass which was recognized as a schwannoma at pathological examination. Tracheotomy was closed 2 weeks postoperatively. After 18 months of followup, the patient is alive and free of disease and her voice had improved markedly.
    Full-text · Article · Jan 2012 · Case Reports in Medicine
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    ABSTRACT: Minithyrotomy is a novel approach that provides direct access to the lamina propria and vocalis muscle without requiring incision of the vocal fold mucosa. The aim of this study was to demonstrate the efficacy of minithyrotomy vocal fold augmentation in a rabbit model by comparing the vocal fold total square amount and the density of scars between the cordotomy with minithyrotomy group and a cordotomy without minithyrotomy group. Animal study. Twenty adult laboratory-conditioned female rabbits were used for this study. Minithyrotomy vocal fold augmentation was performed using a single fat block implant 3 months after cordotomy. To compare total square amount and density of vocal folds between the minithyrotomy and cordotomy group, hematoxylin and eosin, Masson's trichrome, and alcian blue staining was used. Histological examinations showed that minithyrotomy vocal fold augmentation postoperatively restored vocal fold bulkiness and maintained volume for up to 6 months, compared with the cordotomy group (P<0.05). In light of the surgical manipulation, the procedure also did not aggravate scarring of the cordectomized vocal fold. Minithyrotomy vocal fold augmentation using an autologous fat block may soon be feasible in humans undergoing rehabilitation for postcordotomy dysphonia without causing additional damage to the vocal folds.
    No preview · Article · Aug 2011 · Journal of voice: official journal of the Voice Foundation
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