Sustained Profile of Transmitted Drug Resistance Mutations for More Than 10 Years in an HIV Type 1-Infected Patient

Hospital Universitario 12 de Octubre, Madrid, Spain.
AIDS research and human retroviruses (Impact Factor: 2.33). 10/2010; 27(1):41-5. DOI: 10.1089/aid.2010.0104
Source: PubMed


We present an HIV-1-infected patient with a profile of transmitted drug resistance (RT M41L, E44D, V118I, L210W, T215D) sustained during more than 10 years in the absence of treatment. Clonal analysis of different plasma and cellular samples within this period did not reveal any reversion to the wild-type genotype.

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