Disseminated Intravascular Coagulation with Intracranial Haematoma in Neonatal Congenital Syphilis

ArticleinJournal of Tropical Pediatrics 57(4):315-8 · October 2010with19 Reads
Impact Factor: 1.26 · DOI: 10.1093/tropej/fmq088 · Source: PubMed


    Disseminated intravascular coagulation (DIC) although a well known complication in neonatal sepsis is extremely rare in congenital
    syphilis and there are scanty reports of this entity in the literature. Intracranial bleeding following DIC in neonatal congenital
    syphilis is even rarer, and has been reported only once earlier. We are reporting the second case of neonatal DIC with intracranial
    haematoma due to congenital syphilis in a newborn. Our patient also had clinical and biochemical evidence of hepatitis which
    predisposes to DIC. Extensive investigations and emergent use of imaging modalities including ultrasound and CT scan led to
    early diagnosis and treatment in our patient, who could therefore be salvaged from an otherwise life threatening disease.