Vitamin D Status of Inuit Preschoolers Reflects Season and Vitamin D Intake

School of Dietetics and Human Nutrition, McGill University, Montreal H9X 3V9, Quebec, Canada.
Journal of Nutrition (Impact Factor: 3.88). 10/2010; 140(10):1839-45. DOI: 10.3945/jn.110.124644
Source: PubMed


Rickets ascribed to hypovitaminosis D remains a public health concern among Aboriginal children in Canada and the United States. Our primary objective in this study was to investigate the prevalence and risk factors (gender, age, vitamin D intake, and socioeconomic status) for low vitamin D status of Inuit preschoolers living in 16 Arctic communities (51(o)N-70(o)N) and participating in the 2007-2008 Nunavut Child Inuit Health Survey. Children were selected randomly in summer (n = 282) and a follow-up was performed in winter for a subsample (n = 52). Dietary intake was assessed through the administration of a 24-h dietary recall and a FFQ. Anthropometric measurements (height, weight) were assessed. Plasma 25-hydroxy vitamin D was measured using a chemiluminescent assay (Liaison, Diasorin). Prevalence of vitamin D insufficiency (<75 nmol/L) among preschoolers was 78.6% and 96.8% in summer and winter, respectively. Median vitamin D concentrations and interquartile ranges in summer and winter were 48.3 (32.8-71.3) and 37.7 (21.4-52.0) nmol/L, respectively. The prevalence of vitamin D deficiency < 25 and < 37.5 nmol/L was 13.6 and 36.5%, respectively. Children who met or exceeded the adequate intake, those who consumed 2 or more milk servings (1 serving = 250 mL), and those who lived in households without crowding (47.7%) had a better vitamin D status than those who did not. The predictors of vitamin D status were dietary intake and age. Given low traditional food consumption and low consumption of milk, interventions promoting vitamin D supplementation may be required.

Full-text preview

Available from:
  • Source
    • "RUSSIAN JOURNAL OF GENETICS: APPLIED RESEARCH Vol. 4 No. 5 2014 KOZLOV et al. Canada and Greenland (Hayek et al., 2010; Lebrun et al., 1993; Weiler et al., 2006), as well as individuals from the northern regions of the Komi Republic (Potolycina et al., 2010). On the other hand, there is increasing data showing high 255OHD3 content in northern individuals with a traditional style of life and nutrition compared to urbanized individuals (Blazeevich et al., 1983; Kozlov, Ateeva, 2011; Rejnn mark et al., 2004). "
    [Show abstract] [Hide abstract]
    ABSTRACT: The relationship between the vitamin D receptor gene (VDR) variants with serum 25-OHD3 concentration, body height (BH), body weight (BW), and body composition were examined in the Komi ethnic group. The FF-genotype was associated with higher BW (p = 0.002) and lower bone mass (BM, p = 0.06) in comparison to the Ff-genotype carriers. The BB-genotype carriers were characterized by lower BL compared to those with Bb-genotype (p = 0.037); BM was lower among those having bb rather than Bb variants (p = 0.025). No differences in the 25-OHD3 content were revealed. The results are consistent with the data obtained for populations from North-Western Europe and opposite to those reported for tropical and subtropical Caucasians, as well as for non-Caucasians groups.
    Full-text · Article · Sep 2014 · Russian Journal of Genetics: Applied Research
  • Source
    • "Life in the Arctic environment poses special challenges to vitamin D homeostasis (17,37). Hunter populations have lived in Greenland for a thousand years without vitamin D supplementation. "
    [Show abstract] [Hide abstract]
    ABSTRACT: Vitamin D status influences skeletal health, the risk of falls and fractures, and muscle health, and it has been associated with inflammatory, infectious, cardiovascular and metabolic disorders in addition to some cancers. Prevailing intracellular infections such as tuberculosis are speculated to relate to vitamin D status. The vitamin D sources are dietary and dermal, the latter depending on UVB radiation exposure from the sun. Life in the Arctic influences vitamin D status because of dietary peculiarities, the polar night, waning of the ozone layer and maybe ethnic differences between Inuit and non-Inuit. Data on vitamin D status as estimated by plasma 25OHD in Inuit and non-Inuit in Greenland are reviewed. Decreasing intake of vitamin D-rich local food items associated with decreasing plasma 25OHD levels and insufficient vitamin D status is seen with low intake of traditional Inuit foods. Plasma 25OHD levels increase markedly during spring and summer in parallel with the high influx of sunlight while plasma 25OHD is not influenced by obesity in Greenland Inuit and no clear-cut association is seen between plasma 25OHD and the risk of tuberculosis. The frequency of vitamin D deficiency in populations in Greenland rises with the dietary transition and diseases related to low vitamin D status should be monitored.
    Full-text · Article · Aug 2013
  • Source
    • "The nutritional adequacy of Inuit women's diets during pregnancy and while lactating was assessed along with access to traditional foods. Deficiencies were present in magnesium, zinc, calcium, folate, and vitamins E, A, C (54,55), and D (56). One study demonstrated that traditional food contributed more to the diets of older Inuit women (aged 40–74) compared to younger Inuit women (18–39), where market food provided more to women's energy intake (57). "
    [Show abstract] [Hide abstract]
    ABSTRACT: Inuit Canadians are on average about 20 years younger and have a 10-year lower life expectancy than other Canadians. While there have been improvements in Inuit health status over time, significant health disparities still remain. This paper will review the peer-reviewed literature related to Inuit child, youth, and maternal health between 2000 and 2010, investigate which thematic areas were examined, and determine what proportion of the research is related to each group. Establishing areas of research concentrations and scarcities may help direct future research where it is needed. We followed a systematic literature review and employed peer-reviewed research literature on child, youth, and maternal health which were selected from 3 sources, MEDLINE, CINAHL, and the Circumpolar Health Bibliographic Database. The resulting references were read, and summarized according to population group and thematic area. The thematic areas that emerged by frequency were: infectious disease; environment/environmental exposures; nutrition; birth outcomes; tobacco; chronic disease; health care; policy, human resources; interventions/programming; social determinants of health; mental health and wellbeing; genetics; injury; and dental health. The 72 papers that met the inclusion criteria were not mutually exclusive with respect to group studied. Fifty-nine papers (82%) concerned child health, 24 papers (33%) youth health, and 58 papers (81%) maternal health. The review documented high incidences of illness and significant public health problems; however, in the context of these issues, opportunities to develop research that could directly enhance health outcomes are explored.
    Full-text · Article · Jul 2012
Show more