Design and Implementation of the Hispanic Community Health Study/Study of Latinos

Division of Cardiovascular Sciences, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Annals of epidemiology (Impact Factor: 2). 08/2010; 20(8):629-41. DOI: 10.1016/j.annepidem.2010.03.015
Source: PubMed


The Hispanic Community Health Study (HCHS)/Study of Latinos (SOL) is a comprehensive multicenter community based cohort study of Hispanics/Latinos in the United States.
The Study rationale, objectives, design, and implementation are described in this report.
The HCHS/SOL will recruit 16,000 men and women who self-identify as Hispanic or Latino, 18 to 74 years of age, from a random sample of households in defined communities in the Bronx, Chicago, Miami, and San Diego. The sites were selected so that the overall sample would consist of at least 2000 persons in each of the following origin designations: Mexican, Puerto Rican and Dominican, Cuban, and Central and South American. The study includes research in the prevalence of and risk factors for heart, lung, blood and sleep disorders, kidney and liver function, diabetes, cognitive function, dental conditions, and hearing disorders.
The HCHS/SOL will (1) characterize the health status and disease burden in the largest minority population in the United States; (2) describe the positive and negative consequences of immigration and acculturation of Hispanics/Latinos to the mainstream United States life-styles, environment and health care opportunities; and (3) identify likely causal factors of many diseases in a population with diverse environmental exposures, genetic backgrounds, and early life experiences.

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    • "The baseline clinical examination (2008e2011) included comprehensive biological (e.g., anthropometrics, blood draw, oral glucose tolerance test, ankle brachial pressure index, electrocardiogram), behavioral (e.g. dietary intake assessed with two 24-h recalls, sleep habits, overnight sleep exam for apneic events) and socio-demographic (e.g., socioeconomic status, migration history) assessments (Lavange et al., 2010; Sorlie et al., 2010). HCHS/SOL selected households with a stratified 2-stage probability sampling design. "
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    ABSTRACT: Sleep is an important pillar of health and a modifiable risk factor for diabetes, stroke and obesity. Little is known of diet and sleep patterns of Hispanics/Latinos in the US. Here we examine eating behavior as a function of sleep duration in a sub-sample of 11,888 participants from the Hispanic Community Health Study/Study of Latinos, a community-based cohort study of Hispanics aged 18-74 years in four US cities. Using a cross-sectional probability sample with self-report data on habitual sleep duration and up to two 24-h dietary recalls, we quantified the Alternative Healthy Eating Index (AHEI-2010) score and intake of selected nutrients related to cardiovascular health. Linear regression models were fit to estimate least-square means of usual nutrient intake of saturated fats, potassium density, fiber, calcium, caffeine and the AHEI-2010 score, a measure of diet quality, by sleep duration adjusting for age, sex, Hispanic/Latino background, income, employment status, education, depressive symptomology, and years lived in the US. Distribution of calories over the day and association with sleep duration and BMI were also examined. Short sleepers (≤6 h) had significantly lower intake of potassium, fiber and calcium and long sleepers (≥9 h) had significantly lower intake of caffeine compared to others sleepers after adjusting for covariates. However no difference in the AHEI-2010 score was seen by sleep duration. Significantly more long sleepers, compared to intermediate and short sleepers, reported having ≥30% total daily calories before bedtime. Not consuming a snack or meal within 3 h before bedtime was associated with higher AHEI-2010 scores These findings identify novel differences in dietary patterns among short and long sleepers in a Hispanic/Latino population in the U.S. CLINICALTRIALS. NCT02060344. Copyright © 2015. Published by Elsevier Ltd.
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    • "The HCHS/SOL is a national cohort study that aims to establish the prevalence and risk factors for major chronic diseases among 16,415 Hispanics/Latinos recruited from four U.S. field centers (Miami, FL; San Diego, CA; Bronx, NY; Chicago, IL). The sampling strategy (LaVange et al., 2010) and approach (Sorlie et al., 2010) have been detailed elsewhere. The HCHS/SOL Sociocultural Ancillary Study performed a separate, comprehensive assessment of socioeconomic, cultural, and psychosocial factors among approximately one third of the original cohort, with a target sample of 1,320 participants per field center. "
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    ABSTRACT: The Interpersonal Support Evaluation List-12 (ISEL-12; Cohen, Mermelstein, Kamarck, & Hoberman, 1985) is broadly employed as a short-form measure of the traditional ISEL, which measures functional (i.e., perceived) social support. The ISEL-12 can be scored by summing the items to create an overall social support score; three subscale scores representing appraisal, belonging, and tangible social support have also been proposed. Despite extensive use, studies of the psychometric properties of ISEL-12 scores have been limited, particularly among Hispanics/Latinos, the largest and fastest growing ethnic group in the United States. The current study investigated the reliability and structural and convergent validity of ISEL-12 scores using data from 5,313 Hispanics/Latinos who participated in the Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study. Participants completed measures in English or Spanish and identified their ancestry as Dominican, Central American, Cuban, Mexican, Puerto Rican, or South American. Cronbach's alphas suggested adequate internal consistency for the total score for all languages and ancestry groups; coefficients for the subscale scores were not acceptable. Confirmatory factor analyses revealed that the one-factor and three-factor models fit the data equally well. Results from multigroup confirmatory factor analyses supported a similar one-factor structure with equivalent response patterns and variances between language groups and ancestry groups. Convergent validity analyses suggested that the total social support score related to scores of social network integration, life engagement, perceived stress, and negative affect (depression, anxiety) in the expected directions. The total score of the ISEL-12 can be recommended for use among Hispanics/Latinos. (PsycINFO Database Record (c) 2013 APA, all rights reserved).
    No preview · Article · Dec 2013 · Psychological Assessment
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    • "Study variables and their instruments were selected to provide a comprehensive overview of the major determinants of cardiometabolic risk and included physiological, psychosocial, cultural, familial, and behavioral variables (Table 2). Complete characterization of parents' own risk profile is available from the HCHS/SOL baseline examination [22]. "
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    ABSTRACT: This article describes the design and methodology of the Study of Latino Youth (SOL Youth) study, a multicenter study of Hispanic/Latino children living in the United States. Participants are children aged 8-16 years whose parents/legal guardians participated in the Hispanic Community Health Study/Study of Latinos, a large community-based cohort study of Hispanic/Latino adults living in the United States. Between 2012 and 2014, 1600 children recruited from four field centers (Bronx, Chicago, Miami, and San Diego) will undergo a 3.5-hour examination to collect biospecimens, obtain anthropometric measures, blood pressure, fitness level, dietary intake, and physical activity. Psychosocial and environmental characteristics are assessed by questionnaire. Primary study aims are to examine associations of youth's lifestyle behaviors and cardiometabolic risk factors with (1) youth's acculturation and parent-child differences in acculturation; (2) parenting strategies, family behaviors, and parental health behaviors; and (3) youth's psychosocial functioning. SOL Youth will determine the prevalence and distribution of obesity-promoting lifestyle behaviors, cardiometabolic risk profiles, and novel biomarkers associated with obesity and insulin resistance. This article describes the study methodology and considers advantages and limitations of embedding a cohort of children within a well-characterized cohort of adults.
    Full-text · Article · Oct 2013 · Annals of epidemiology
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