Onset of Catatonia at Puberty Electroconvulsive Therapy Response in Two Autistic Adolescents

Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109-5734, USA.
The journal of ECT (Impact Factor: 1.39). 12/2010; 26(4):274-7. DOI: 10.1097/YCT.0b013e3181de332e
Source: PubMed


Catatonia is a syndrome of motor and behavioral disturbance. It is a poorly understood condition, which is underrecognized and may go untreated despite intensive medical workup and numerous unsuccessful medication trials. However, with treatments known to be effective, such as benzodiazepines and/or electroconvulsive therapy, patients may return to their baseline functioning. Autism and catatonia have been previously reported together. We report 2 patients with autism and mental retardation who developed catatonic symptoms at the onset of puberty. Both patients experienced persistent symptoms over several years and presented with a history of motor disturbance, functional decline, and episodic aggression. Both patients were treated with electroconvulsive therapy resulting in a positive response and functional improvement. Catatonia may persist as a chronic condition, lasting over several months or years, if not recognized and treated.

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Available from: Daniel Gih, Mar 04, 2014
    • "We carried out a search in PubMed and could locate 10 reports[6789101112131415] of use of ECT in adolescents with catatonia published after the review of Consoli et al.[4] Eight out of the 10 reports, described 11 cases in which ECT was used in adolescents for treatment of catatonia in patients with varied clinical conditions [Table 2].[678910111213] One case series described the use of maintenance ECT in three children with autism, in which ECT had led to resolution of acute symptoms of catatonia.[14] "
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    ABSTRACT: There is lot of skepticism about the use of electroconvulsive therapy (ECT) in children and adolescents. However, available literature suggests that use of ECT can be at times life-saving in adolescents, especially those presenting with severe catatonia. We treated a 16-year-old female who presented to us with catatonia with a course of nine ECTs, with which she showed marked improvement. Review of the literature suggests that ECT should be considered as the second line treatment in the management of catatonia in adolescents.
    No preview · Article · Apr 2014 · Indian Journal of Psychological Medicine

  • No preview · Article · Dec 2010 · The journal of ECT
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    ABSTRACT: Autism spectrum disorders (ASD), labeled as pervasive developmental disorders (PDD) in the DSM-IV-TR (APA, 2000), are characterized by a distinct pattern of social and communication deficits with rigid ritualistic interests. While autism (Kanner, 1943) is the main category, other conditions include Asperger syndrome (Asperger, 1944) and pervasive developmental disorder not otherwise specified (PDDNOS). Rett disorder and childhood disintegrative disorder, although classified in the same category, are often not referred to as ASDs. As discussed elsewhere in this volume, the DSM-V is likely to collapse autism, Asperger syndrome, and PDDNOS into a single category called ASD.
    No preview · Chapter · Dec 2010
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