Triterpenoids from the leaves of Toona ciliata

State Key Laboratory of Phytochemistry and Plant Resources in West China,, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.
Journal of Asian natural products research (Impact Factor: 0.91). 06/2010; 12(6):448-52. DOI: 10.1080/10286020.2010.493329
Source: PubMed


One new limonoid, toonaciliatone A (1), and one new tirucallane-type triterpenoid, toonaciliatine A (4), along with three known compounds, methyl-3beta-acetoxy-1-oxomelic-14(15)-enate (2), perforin A (3), and cholest-14-ene-3,7,24,25-tetrol-21,23-epoxy-21-methoxy-4,4,8-trimethyl-3-(3-methyl-2-butenoate) (5), were isolated from the leaves of Toona ciliata. The structures of the new compounds were established by spectroscopic methods.

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    • "T. sinensis has also been shown to inhibit steroidogenesis in Leydig cells (Poon, Leu, Hsu, Liu, & Huang, 2005) and improve sperm activity (Wang, Hsu, Hsu, Liao, & Chan, 2005). A variety of phytochemical components have been isolated and characterized from T. sinensis leaves, some of these include adenosine, gallic acid, methyl gallic acid, 3-O-b-D-(60-O 0 Galloyl)-glucopyranoside , 4-O-b-D-(60-O 0 Galloyl)-glucopyranoside, methyl gallate, ethyl gallate, kaempferol, kaempferol-3-O-b-glucoside, quercitrin, quercetin-3-O-b-glucoside, rutin, and catechin (Cheng et al., 2009; Li, Mo, & Ning, 2009; Ning et al., 2010). Scientists are dedicated to discovering novel drugs that target tumour cells without being toxic to normal cells. "
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