Autophagy Shows Its Animal Side

Department of Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Cell (Impact Factor: 32.24). 06/2010; 141(6):922-4. DOI: 10.1016/j.cell.2010.05.036
Source: PubMed


Most autophagy genes have been discovered in the single-celled yeast Saccharomyces cerevisiae, and little is known about autophagy genes that are specific to multicellular animals. In this issue, Tian et al. (2010) now identify four new autophagy genes: one specific to the nematode Caenorhabditis elegans and three conserved from worms to mammals.

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