Allergic contact dermatitis to propyl gallate and pentylene glycol in an emollient cream. Australas J Dermatol

Department of Internal Medicine, Immunology and Infectious Diseases, Dermatology Clinic, University of Bari, Bari, Italy.
Australasian Journal of Dermatology (Impact Factor: 1.11). 05/2010; 51(2):147-8. DOI: 10.1111/j.1440-0960.2009.00618.x
Source: PubMed


A 62-year-old man, with a 20-year history of seborrhoeic dermatitis, presented with a worsening of his dermatitis. He had previously been demonstrated to be allergic to various topical corticosteroids, so he had been using an emollient cream (Sebclair), containing piroctone olamine and various anti-inflammatory substances, for 6 months, with good effect. Patch testing to the cream and its ingredients revealed positive reactions to both propyl gallate and pentylene glycol. A positive reaction to propylene glycol was also detected, whereas patch testing to butylene glycol was negative. Complete remission followed avoidance of the offending substances.

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