When Is the Helix Conformation Restored after the Reverse Reaction of Phototropin?

ArticleinJournal of the American Chemical Society 132(26):8838-9 · July 2010with6 Reads
Impact Factor: 12.11 · DOI: 10.1021/ja1020519 · Source: PubMed

    Abstract

    Following the disruption of the covalent bond between the cysteine and flavin of Phot1LOV2-linker, the unfolded conformation of the linker folds with a time constant of 13 ms, which is considerably (approximately 10(4) times) slower than the helix formation rate measured for an alpha-helical polypeptide in solution.