Challenges of treating asthma in people who smoke

ArticleinExpert Review of Clinical Immunology 6(2):257-68 · March 2010with17 Reads
Impact Factor: 2.48 · DOI: 10.1586/eci.09.85 · Source: PubMed


    Cigarette smoking is common in asthma and is associated with poor symptom control and a reduced therapeutic response to inhaled and oral corticosteroids as compared with nonsmokers with asthma. This review examines the range of adverse health effects of smoking in asthma, the inflammatory mechanisms that may influence the efficacy of current drugs and discusses potential future therapeutic directions.