Article

Comprehensive cardiac magnetic resonance approach to assess myocardial involvements in asymptomatic patients with rheumatic diseases: comparison of MRI findings between rheumatic arthritis and systemic sclerosis

Journal of Cardiovascular Magnetic Resonance (Impact Factor: 4.56). 01/2010; 12(Suppl 1). DOI: 10.1186/1532-429X-12-S1-P181
Source: DOAJ

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Available from: Yasuo Nakajima, Mar 29, 2016
BioMed Central
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Journal of Cardiovascular Magnetic
Resonance
Open Access
Poster presentation
Comprehensive cardiac magnetic resonance approach to assess
myocardial involvements in asymptomatic patients with rheumatic
diseases: comparison of MRI findings between rheumatic arthritis
and systemic sclerosis
Kobayashi Yasuyuki*
1
, Isamu Yokoe
2
, Masahiro Hirano
3
, Yasuo Nakajima
1
,
John T Giles
4
and Hitomi Kobayashi
2
Address:
1
St.Marianna University School of Medicine, Kawasaki, Japan,
2
Itabashi Chuo Medical Center, Tokyo, Japan,
3
Tokyo Medical University,
Tokyo, Japan and
4
Johns Hopkins University School of Medicine, Baltimore, Japan
* Corresponding author
Introduction
Rheumatic Disease is a multi-organ inflammatory disor-
der associated with high cardiovascular morbidity and
mortality.
Purpose
We assessed myocardial involvements by using a compre-
hensive cardiac magnetic resonance imaging (cMRI) with
stress/rest perfusion and delayed enhancement in asymp-
tomatic patients with rheumatic arthritis (RA) and sys-
temic sclerosis (SSc).
Methods
18 RA and nine SSc patients with no history and/or clini-
cal findings of cardiac disorders underwent cMRI on a 1.5
T scanner. Adenosine triphosphate was used for stress per-
fusion to assess perfusion defect (PD), and delayed
enhancement (DE) imaging was obtained. We assessed
the efficacy of cMRI and compared the prevalence of myo-
cardial involvements in the patients with RA to SSc.
Results
1) RA: Stress PDs were seen in two out of 18 RA patients
(11%), one of whom had circumferential subendocardial
PD and one had a non-segmental subendocardial PD.
Seven patients were found to have DE (39%). DE was
observed in six without PD and one patient with PD dem-
onstrated DE. Five had a DE in the middle or subepicar-
dial layer. The remaining two had a subendcardial DE in
segment.2) SSc: Stress PDs were seen in five out of nine
SSc patients (56%), four of whom had non-segmental
subendocardial perfusion defects and one had a segmen-
tal subendocardial perfusion defect. Three patients were
found to have DE (33%). DE was not observed in any
patient without perfusion defect and among the five
patients with perfusion defects, three (60%) demon-
strated delayed enhancement. Two of the three had non-
segmental DE in the middle l layer and one had segmental
subendocardial DE.
Conclusion
Subclinical myocardial involvements were frequent in
asymptomatic patients with RA and SSc. Comprehensive
cMRI is considered to be a feasible diagnostic method for
assessing myocardial involvement in asymptomatic
patients with RD.
from 13th Annual SCMR Scientific Sessions
Phoenix, AZ, USA. 21-24 January 2010
Published: 21 January 2010
Journal of Cardiovascular Magnetic Resonance 2010, 12(Suppl 1):P181 doi:10.1186/1532-429X-12-S1-P181
<supplement> <title> <p>Abstracts of the 13<sup>th </sup>Annua l SCMR Scientific Sessions - 2010</p> </ti tle> <note>Meeting abstracts - A single PDF containing all abstracts in this Supplement is available <a href="http://www.biomedcentral.com/content/files/pdf/1532-429X-11-S1-full.pdf">here</a>.</note> <url>http://www.biomedcentral.com/content/files/pdf/1532-429X-11-S1-info</url> </supplement>
This abstract is available from: http://jcmr-online.com/content/12/S1/P181
© 2010 Yasuyuki et al; licensee BioMed Central Ltd.
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