Sequence types and antimicrobial susceptibility of invasive Streptococcus pneumoniae isolates from a region with high antibiotic selective pressure and suboptimal vaccine coverage

ArticleinThe Pediatric Infectious Disease Journal 29(5):467-9 · December 2009with2 Reads
Impact Factor: 2.72 · DOI: 10.1097/INF.0b013e3181cb45f3 · Source: PubMed


    Multilocus sequence typing was carried out on 95 invasive pneumococcal isolates belonging to the most common 7 serotypes currently circulating in Taiwan. The study confirmed continued prevalence in Taiwan of a few global clones and sequence types (STs) since the mid-1990s and identified the recent emergence of ST320 (19A) and ST902 (6A). Antimicrobial nonsusceptibility was common in the predominant STs of serotypes 14, 19A, 19F, and 23F.