Inflammatory breast cancer: What are the treatment options?
University of Michigan, Comprehensive Cancer Center, Department of Internal Medicine, Ann Arbor, 48109-0948, USA.Expert Opinion on Pharmacotherapy (Impact Factor: 3.53). 12/2009; 10(18):2987-97. DOI: 10.1517/14656560903401638
An otherwise healthy, 68-year-old woman presents to her primary-care physician complaining of right breast enlargement, warmth, and progressive pink to dark red skin changes over the past month. She denies fever, pain, or breast discharge. Physical examination reveals erythema of the whole right breast, warmth, swelling, induration, and nipple retraction. Palpable axillary lymphadenopathy is appreciated on the right only. The left breast is uninvolved. The physician is concerned that she may have inflammatory breast cancer.
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ABSTRACT: Inflammatory breast cancer (IBC) is the most aggressive form of locally advanced breast cancer. We present here (18)F FDG PET/CT findings of two patients with IBC. These patients were referred to the Nuclear Medicine department for staging of IBC. FDG PET/CT images showed diffuse infiltration of breasts with multiple lymph nodes and multiple metastases in whole-body PET/CT images. FDG PET provides additional information regarding lymph nodes or distant metastases in the initial evaluation of IBC.
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