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Quality & Quantity
https://doi.org/10.1007/s11135-025-02126-6
Analyzing anxiety andtreatment trends using google trends:
validation ofepidemiologic studies andforecasting
RezaJafarzadehEsfehani1 · AmirRezaeiArdani2· AfsanehRezaeiKalat3
Accepted: 8 March 2025
© The Author(s), under exclusive licence to Springer Nature B.V. 2025
Abstract
Anxiety disorders are among the most prevalent mental health conditions globally, and
studying their trends helps societies provide better care and prevention plans. The pre-
sent study aimed to explore the global trend of anxiety disorders and antianxiety medi-
cation-related terms using Google Trend analysis and forecast future trends. A Google
Trend analysis was performed on specific search terms related to anxiety disorders from
June 2005 to August 2023. Curve estimation regression analysis was conducted for the
five main categories, and the Expert Modeler in SPSS software was used to model the
data. Auto-Regressive Integrated Moving Average was applied for forecasting. Our model
for anxiety-related search terms over the internet accurately predicted trends reported by
the World Health Organization. The seasonally adjusted model for anxiety-related terms,
BNZs, SSRIs, gabapentin, trazodone, and the sum of all drugs estimated changes of 16.8%,
− 44.9%, 18.2%, 67.3%, 36.6%, and 16.8% respectively, from August 2023 to January
2030. Searches for anxiety-related terms and medications have shown an increasing trend
since 2005. The forecasting model indicates a 16% rise in general anxiety searches from
2023 to 2030, with medication-related terms predicted to increase more rapidly.
Keywords Anxiety· Selective serotonin reuptake inhibitors· Benzodiazepines
* Afsaneh Rezaei Kalat
rezaeiafs69@gmail.com
Reza Jafarzadeh Esfehani
drrezajafarzadeh@yahoo.com; jafarzadeh@acecr.ac.ir
Amir Rezaei Ardani
rezaeia@mums.ac.ir
1 Blood Borne Infections Research Center, Academic Center forEducation, Culture & Research
(ACECR), Razavi Khorasan Branch, Mashhad, Iran
2 Department ofPsychiatry, Southwest Centre forForensic Mental Health Care, Schulich School
ofMedicine & Dentistry, University ofWestern Ontario, London, ON, Canada
3 Psychiatry andBehavioral Sciences Research Center, Ibne-Sina Hospital, Mashhad University
ofMedical Sciences, Buali Square, Mashhad, Iran
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