On February 6, 2023, two major earthquakes occurred in southern Turkey with an interval of 9 hours. The two earthquakes that occurred are two major earthquakes that are individually important. If it had occurred in different regions over a longer period, it would have entered the literature as two separate earthquakes. These two major earthquakes, centered in Pazarcik (7.7 Mw) and Elbistan (7.6 Mw), affected a total of 11 cities in the south and east of the country, and approximately 14 million people living in these cities were directly damaged by the earthquake. According to the official data, the loss of life due to the earthquake is around 50000. After the earthquake that caused such great losses, the region became the focus of researchers. However, studies focus on structural damage, considering the earthquake's first effect. Although not directly caused by the first movement after the earthquake, secondary effects resulting from the earthquake or the physical characteristics of the region cause significant damage, although not as much as the primary effects. Secondary effects such as liquefaction, fire, landslide, change in water level, change in water quality, surface fractures, and tsunami should be examined and prevented from occurring in these situations as well as buildings affected by earthquakes. Within the scope of this study, the type and distribution of secondary effects in the cities affected by the Kahramanmaraş earthquakes were examined. Secondary effects were intense in the cities of Hatay, Kahramanmaraş, Adiyaman and Malatya. In addition to the distribution of secondary effects, its relationship with the rate of structural damage and the economic costs it causes were examined. Considering the results, the incidence of secondary effects also increases in cities with a high rate of structural damage. In addition, the effect of secondary effects on direct economic costs is around 30%. The economic cost of the Kahramanmaraş earthquakes due to secondary effects has been calculated as approximately 17 billion dollars. In addition to the primary effects of earthquakes, their secondary effects should also be considered. This will give sensitivity to the predictions made in terms of minimizing earthquake-related damage.