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Supplementary appendix 1.pdf

April 2024

Authors:

Alize J Ferrari

The University of Queensland

Yohannes Habtegiorgis

Aleta Wondo Hospital

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Conference Paper

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Statin use for primary prevention of cardiovascular diseases among an urban Sri Lankan cohort of pat...

November 2019

Chamila Mettananda

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Article

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Antiplatelet therapy for transient ischaemic attacks and acute minor strokes: current best practice...

June 2021 · Journal of the Ceylon College of Physicians

Chamila Mettananda

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Conference Paper

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Title CAROTID ARTERY STENOSIS IN PATIENTS WITH ISCHAEMIC STROKE IN A TERTIARY CARE CENTRE: PREVALENC...

September 2019

Chamila Mettananda

Objectives Data on the prevalence of carotid artery stenosis (CAS) among Sri Lankan stroke patients is limited. We sought to determine the prevalence and associated factors of significant CAS in patients with ischaemic stroke admitted to a Sri Lankan stroke unit. Methods We prospectively studied all stroke patients admitted to a stroke unit in a tertiary care hospital over a five-year period. ... [Show full abstract] Presence and degree of CAS was evaluated by doppler ultrasonography (US). Degree of CAS was classified as low (<50%), moderate (50-69%), significant (70-99%) or total occlusion (100%) according to NASCET criteria. Factors associated with CAS ≥ 70% were identified by stepwise multiple logistic regression analysis. Results Out of 867 stroke patients studied, 704 (81.2%) had ischaemic strokes (59.7% male, mean age 59.0±10.3 years), and 550 (78.1%) of them had carotid doppler data available. 528 (96.0%) had low degree stenosis, 12 (2.2%) had moderate stenosis, 7 (1.3%) had significant stenosis and 3 (0.5%) had total occlusion. Older age was associated with significant CAS (OR 1.14, p=0.011) on stepwise multiple logistic regression analysis. Sex, smoking, BMI, total cholesterol, LDL cholesterol, history of diabetes mellitus, hypertension, hyperlipidaemia or ischemic heart disease, and premorbid aspirin or statin use were not associated with significant CAS. Conclusions Significant CAS is seen in only 1.8% of Sri Lankan patients with ischaemic stroke at this tertiary care centre. These figures are much lower compared to Western data. Our findings have implications for the use of management approaches such as thrombectomy and carotid endarterectomy in Sri Lankan patients. Acknowledgements-EMDP and WLM were supported by a research grant from the National Stroke Association of Sri Lanka.

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Preprint

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Antiplatelet therapy for transient ischaemic attacks and acute minor strokes: current best practice...

November 2020

Chamila Mettananda

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Last Updated: 18 Apr 2025

Supplementary appendix 1.pdf

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